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[力克舒胶囊中对乙酰氨基酚、咖啡因及盐酸麻黄碱的含量测定]

[Determination of paracetmol caffeine and ephedrine hydrochloride in likeshu capsules].

作者信息

Wu C, Zhou Z, Zhao H

出版信息

Hua Xi Yi Ke Da Xue Xue Bao. 1995 Dec;26(4):443-6.

PMID:8732071
Abstract

Paracetamol (P), caffeine (C) and ephedrine hydrochloride (EH) are there physiological active component in Likeshu capsules. We have proposed the determination method of these three components using extractive separation-spectrophotometry. Only one amount weighed of sample is required to determine them. The recoveries of P, C and EH were 97.51 +/- 0.64% (n = 9), 98.24 +/- 1.04% (n = 8) and 98.58 +/- 1.09% (n = 9) respectively. The results of determination of samples agreed with those of the HPLC method. This method is sensitive, accurate and simple. The other ingredients of Likeshu capsules do not interfere.

摘要

力克舒胶囊中含有对乙酰氨基酚(P)、咖啡因(C)和盐酸麻黄碱(EH)这三种生理活性成分。我们提出了采用萃取分离-分光光度法测定这三种成分的方法。只需称取一份样品量即可对它们进行测定。P、C和EH的回收率分别为97.51±0.64%(n = 9)、98.24±1.04%(n = 8)和98.58±1.09%(n = 9)。样品的测定结果与高效液相色谱法的结果一致。该方法灵敏、准确且简便。力克舒胶囊中的其他成分不产生干扰。

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