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香叶天竺葵挥发油的化学成分及抗肿瘤作用研究

[Studies on the chemical components and anti-tumour action of the volatile oils from Pelargonium graveoleus].

作者信息

Fang H J, Su X L, Liu H Y, Chen Y H, Ni J H

出版信息

Yao Xue Xue Bao. 1989;24(5):366-71.

PMID:2609972
Abstract

Three geranium oils were separated, identified and compared by high resolution cross-linked fused silica capillary GC and GC-MSD. It was found that their chemical constituents are very similar, but the contents of some components (linalool, citronellol, cis-caryophyllene and guaiene) differ appreciably. Pharmacological experiments showed that citronellol, citronellyl formate, geraniol and citronellyl acetate exhibited marginal antitumour activities. The activity of the latter two components has not been reported in the literature.

摘要

采用高分辨率交联熔融石英毛细管气相色谱法和气相色谱-质谱联用仪对三种天竺葵油进行了分离、鉴定和比较。结果发现,它们的化学成分非常相似,但某些成分(芳樟醇、香茅醇、顺式石竹烯和愈创木烯)的含量有明显差异。药理实验表明,香茅醇、甲酸香茅酯、香叶醇和乙酸香茅酯具有微弱的抗肿瘤活性。后两种成分的活性在文献中尚未见报道。

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