Bhatara V, Arnold L E, Knopp W, Smeltzer D J
Psychopharmacology (Berl). 1978 Apr 28;57(2):185-7. doi: 10.1007/BF00426885.
To confirm the conclusions from a previous study supporting the usefullness of electropupillogram (E.P.G.) in predicting clinical response, data from three separate studies with hyperkinetic and learning disabled (L.D.) children treated with stimulants were surveyed. Change in extent of pupillary contraction (E.C.) after a test dose of stimulant as measured by E.P.G. did not correlate significantly with actual clinical rating change (with one exception out of 14 correlations calculated). These negative results are reported with a reservation regarding their validity because of technical difficulties in data collection.
为证实先前一项支持眼电图（E.P.G.）在预测临床反应中有用性的研究所得出的结论，我们对三项分别针对使用兴奋剂治疗的多动和学习障碍（L.D.）儿童的研究数据进行了调查。通过E.P.G.测量，给予测试剂量兴奋剂后瞳孔收缩程度（E.C.）的变化与实际临床评分变化并无显著相关性（在计算的14个相关性中仅有一个例外）。由于数据收集存在技术困难，这些负面结果在报告时对其有效性有所保留。
