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糖化血红蛋白水平升高与2型糖尿病患者的SYNTAX评分II相关。

Increased Glycated Hemoglobin Level is Associated With SYNTAX Score II in Patients With Type 2 Diabetes Mellitus.

作者信息

Karakoyun Süleyman, Gökdeniz Tayyar, Gürsoy Mustafa Ozan, Rencüzoğulları İbrahim, Karabağ Yavuz, Altıntaş Bernas, Topçu Selim, Lazoğlu Zakir, Tanboğa İbrahim Halil, Sevimli Serdar

机构信息

Department of Cardiology, Kafkas University Medical School, Kars, Turkey

Department of Cardiology, Kafkas University Medical School, Kars, Turkey.

出版信息

Angiology. 2016 Apr;67(4):384-90. doi: 10.1177/0003319715591752. Epub 2015 Jun 22.

Abstract

SYNTAX score II (SS II) uses 2 anatomical and 6 clinical variables for the prediction of mortality after coronary artery bypass graft and percutaneous coronary intervention. The aim of this study was to investigate the relationship between glycated hemoglobin (HbA1c), fasting blood glucose (FBG), postprandial glucose (PPG), and SYNTAX Score (SS) and SS II in patients with type 2 diabetes mellitus and coronary artery disease (CAD). We enrolled 215 consecutive diabetic patients with stable angina pectoris who underwent coronary angiography. The SS II was calculated using a nomogram that was based on the findings of a previous study. There was a moderate correlation between HbA1c and SS (r = .396, P < .001), but there was a good correlation between HbA1c and SS II (r = .535, P < .001). There was also a weak correlation between FBG (r = .270, P = .001), PPG (r = .177, P = .027), and SS, but there was a weak-moderate correlation between FBG (r = .341, P < .001), PPG (r = .256, P = .001), and SS II. A better correlation has been detected between HbA1c and SS II compared to the correlation between HbA1c and SS.

摘要

SYNTAX评分II(SS II)使用2个解剖学变量和6个临床变量来预测冠状动脉旁路移植术和经皮冠状动脉介入治疗后的死亡率。本研究的目的是调查2型糖尿病合并冠状动脉疾病(CAD)患者糖化血红蛋白(HbA1c)、空腹血糖(FBG)、餐后血糖(PPG)与SYNTAX评分(SS)及SS II之间的关系。我们连续纳入了215例接受冠状动脉造影的稳定型心绞痛糖尿病患者。SS II使用基于先前研究结果的列线图进行计算。HbA1c与SS之间存在中度相关性(r = 0.396,P < 0.001),但HbA1c与SS II之间存在良好相关性(r = 0.535,P < 0.001)。FBG(r = 0.270,P = 0.001)、PPG(r = 0.177,P = 0.027)与SS之间也存在弱相关性,但FBG(r = 0.341,P < 0.001)、PPG(r = 0.256,P = 0.001)与SS II之间存在弱-中度相关性。与HbA1c和SS之间的相关性相比,HbA1c与SS II之间检测到更好的相关性。

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