非糖尿病患者空腹血糖对严重冠状动脉粥样硬化的预测价值。
Predictive value of fasting blood glucose for serious coronary atherosclerosis in non-diabetic patients.
作者信息
Zhao Tong, Gong Hui-Ping, Dong Zhao-Qiang, Du Yi-Meng, Lu Qing-Hua, Chen Hui-Qiang
机构信息
Department of Cardiology, the Second Hospital of Shandong University, Shandong University, Ji-nan, Shandong Province, China.
出版信息
J Int Med Res. 2019 Jan;47(1):152-158. doi: 10.1177/0300060518798252. Epub 2018 Sep 12.
Abstract
OBJECTIVE
To determine if high fasting blood glucose (FBG) level is an independent predictor of serious coronary lesions in patients with coronary artery disease (CAD).
METHODS
We enrolled 64 patients who had symptoms of chest discomfort and who underwent coronary angiography. FBG was determined from blood samples and the extent of coronary artery lesions was analyzed according to Gensini score. We examined the relationships among diabetes, FBG, and coronary artery severity.
RESULTS
Diabetes and FBG were significantly and positively related to Gensini score. Diabetes, but not FBG, was independently correlated with the occurrence of a Gensini score >41. However, FBG was significantly associated with Gensini score >41 in non-diabetic patients.
CONCLUSION
Hyperglycemia is an independent predictor of severe CAD in non-diabetic patients. Clinicians should be aware of this and should carry out appropriate early interventions.
摘要
目的
确定空腹血糖（FBG）水平升高是否为冠心病（CAD）患者严重冠状动脉病变的独立预测因素。
方法
我们纳入了64例有胸部不适症状且接受冠状动脉造影的患者。通过血样测定FBG，并根据Gensini评分分析冠状动脉病变程度。我们研究了糖尿病、FBG与冠状动脉严重程度之间的关系。
结果
糖尿病和FBG与Gensini评分显著正相关。糖尿病而非FBG与Gensini评分>41的发生独立相关。然而，在非糖尿病患者中，FBG与Gensini评分>41显著相关。
结论
高血糖是非糖尿病患者严重CAD的独立预测因素。临床医生应意识到这一点，并应进行适当的早期干预。
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