Mahdizadeh Shahla, Khaleghi Ghadiri Maryam, Gorji Ali
Epilepsy Research Center, Universitätsklinikum Münster, Münster, Germany.
Department of Neurosurgery, Universitätsklinikum Münster, Münster, Germany.
Avicenna J Phytomed. 2015 May-Jun;5(3):182-202.
Naturally occurring substances mentioned in medieval medical literatures currently have, and will continue to have, a crucial place in drug discovery. Avicenna was a Persian physician who is known as the most influential medical writers in the Middle ages. Avicenna`s Canon of Medicine, the most famous books in the history of medicine, presents a clear and organized summary of all the medical knowledge of the time, including a long list of drugs. Several hundred substances and receipts from different sources are mentioned for treatment of different illnesses in this book. The aim of the present study was to provide a descriptive review of all anti-inflammatory and analgesic drugs presented in this comprehensive encyclopedia of medicine. Data for this review were provided by searches of different sections of this book. Long lists of anti-inflammatory and analgesic substances used in the treatment of various diseases are provided. The efficacy of some of these drugs, such as opium, willow oil, curcuma, and garlic, was investigated by modern medicine; pointed to their potent anti-inflammatory and analgesic properties. This review will help further research into the clinical benefits of new drugs for treatment of inflammatory diseases and pain.
中世纪医学文献中提及的天然物质在当前以及未来的药物发现中都将占据关键地位。阿维森纳是一位波斯医生,被誉为中世纪最具影响力的医学作家。阿维森纳的《医典》是医学史上最著名的书籍之一,它清晰且有条理地总结了当时所有的医学知识,其中包括一长串药物清单。这本书中提到了数百种来自不同来源的物质和方剂,用于治疗各种疾病。本研究的目的是对这部综合性医学百科全书中介绍的所有抗炎和镇痛药进行描述性综述。该综述的数据来源于对这本书不同章节的检索。文中提供了用于治疗各种疾病的抗炎和镇痛物质的详细清单。现代医学对其中一些药物的疗效进行了研究,比如鸦片、柳油、姜黄和大蒜,结果表明它们具有强大的抗炎和镇痛特性。这篇综述将有助于进一步研究治疗炎症性疾病和疼痛的新药的临床益处。