Defoor Dewayne L, Vazquez-Quino Luis A, Mavroidis Panayiotis, Papanikolaou Nikos, Stathakis Sotirios
Cancer Therapy and Research Center, Department of Radiation Oncology, University of Texas Health Science Center at San Antonio, TX, 78229, USA.
J Appl Clin Med Phys. 2015 May 8;16(3):5283. doi: 10.1120/jacmp.v16i3.5283.
In this project, we investigated the use of an electronic portal imaging device (EPID), together with the treatment planning system (TPS) and MLC log files, to determine the delivered doses to the patient and evaluate the agreement between the treatment plan and the delivered dose distribution. The QA analysis results are presented for 15 VMAT patients using the EPID measurements, the ScandiDos Delta4 dosimeter, and the beam fluence calculated from the multileaf collimator (MLC) log file. EPID fluence images were acquired in continuous acquisition mode for each of the patients and they were processed through an in-house MATLAB program to create an opening density matrix (ODM), which was used as the input fluence for the dose calculation in the TPS (Pinnacle3). The EPID used in this study was the aSi1000 Varian on a Novalis TX linac equipped with high-definition MLC. The actual MLC positions and gantry angles were retrieved from the MLC log files and the data were used to calculate the delivered dose distributions in Pinnacle. The resulting dose distributions were then compared against the corresponding planned dose distributions using the 3D gamma index with 3 mm/3% passing criteria. The ScandiDos Delta4 phantom was also used to measure a 2D dose distribution for all the 15 patients and a 2D gamma was calculated for each patient using the Delta4 software. The average 3D gamma using the EPID images was 96.1% ± 2.2%. The average 3D gamma using the log files was 98.7% ± 0.5%. The average 2D gamma from the Delta4 was 98.1% ± 2.1%. Our results indicate that the use of the EPID, combined with MLC log files and a TPS, is a viable method for QA of VMAT plans.
在本项目中,我们研究了使用电子射野影像装置(EPID),结合治疗计划系统(TPS)和多叶准直器(MLC)日志文件,来确定患者所接受的剂量,并评估治疗计划与所交付剂量分布之间的一致性。给出了15例容积调强弧形治疗(VMAT)患者使用EPID测量、ScandiDos Delta4剂量仪以及从MLC日志文件计算得到的射束注量的质量保证(QA)分析结果。对每位患者以连续采集模式获取EPID注量图像,并通过内部的MATLAB程序对其进行处理,以创建开放密度矩阵(ODM),该矩阵用作TPS(Pinnacle3)中剂量计算的输入注量。本研究中使用的EPID是配备了高清MLC的瓦里安aSi1000,安装在Novalis TX直线加速器上。从MLC日志文件中获取实际的MLC位置和机架角度,并将这些数据用于在Pinnacle中计算所交付的剂量分布。然后使用具有3 mm/3%通过率标准的三维伽马指数,将所得的剂量分布与相应的计划剂量分布进行比较。还使用ScandiDos Delta4模体测量了所有15例患者的二维剂量分布,并使用Delta4软件为每位患者计算二维伽马值。使用EPID图像的平均三维伽马值为96.1%±2.2%。使用日志文件的平均三维伽马值为98.7%±0.5%。来自Delta4的平均二维伽马值为98.1%±2.1%。我们的结果表明,将EPID与MLC日志文件和TPS结合使用,是VMAT计划QA的一种可行方法。