通过双源计算机断层扫描钙化积分评估主动脉根部钙化严重程度与冠状动脉钙化范围的相关性。
Association of aortic root calcification severity with the extent of coronary artery calcification assessed by calcium-scoring dual-source computed tomography.
作者信息
Hu Xiaohan, Frellesen Claudia, Kerl J Matthias, Bauer Ralf W, Beeres Martin, Bodelle Boris, Lehnert Thomas, Vogl Thomas J, Wichmann Julian L
机构信息
University Hospital Frankfurt, Department of Diagnostic and Interventional Radiology, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.
University Hospital Frankfurt, Department of Diagnostic and Interventional Radiology, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.
出版信息
Eur J Radiol. 2015 Oct;84(10):1910-4. doi: 10.1016/j.ejrad.2015.06.003. Epub 2015 Jun 6.
PURPOSE
To investigate the association between aortic root calcification (ARC) and coronary artery calcification (CAC) assessed by coronary artery calcium-scoring dual-source computed tomography (DSCT).
MATERIALS AND METHODS
We retrospectively analyzed 143 consecutive patients who underwent coronary artery calcium-scoring during coronary DSCT angiography. 57 patients had findings of ARC on calcium-scoring scans. ARC volume (ARCV) and Agatston coronary artery calcium score (CACS) were calculated. Chi-square test was used to assess differences of categorical variables between patients with and without ARC. Statistical significances between both groups were assessed with the independent-Sample t test.
RESULTS
Compared with patients without ARC (n=86), patients with ARC (n=57) showed a significantly higher presence of CAC (87.7% vs. 24.4%; P<0.001), and a higher mean CACS (700.6 ± 941.2 vs. 256.4 ± 724.3; P=0.009) in patients with CAC. Patients with a calculated ARCV > 40 mm(3) (n=32) showed significantly higher rates of severe CAC (56.3% vs. 24.0%; P=0.014) compared with patients with an ARCV< 40 mm(3) (n=25). Compared with patients without CAC (n=42), patients with CAC (n=101) showed a significantly higher presence of ARC (83.3% vs. 50.5%; P<0.001) and a higher mean ARCV (95.4 ± 116.2mm(3) vs. 29.7 ± 33.0 mm(3); P=0.003). Severe CAC (n=24) correlated with an increased mean ARCV (122.3 ± 148.8mm(3)) compared to patients with minimal to moderate CAC (n=33, mean ARCV: 61.9 ± 64.8mm(3); P<0.05).
CONCLUSIONS
The extent of ARC is directly associated with the presence and degree of CAC on calcium-scoring scans during coronary DSCT angiography.
目的
通过冠状动脉钙化积分双源计算机断层扫描（DSCT）研究主动脉根部钙化（ARC）与冠状动脉钙化（CAC）之间的关联。
材料与方法
我们回顾性分析了143例在冠状动脉DSCT血管造影期间接受冠状动脉钙化积分检查的连续患者。57例患者在钙化积分扫描中有ARC表现。计算ARC体积（ARCV）和阿加斯顿冠状动脉钙化积分（CACS）。采用卡方检验评估有ARC和无ARC患者分类变量的差异。两组间的统计学显著性采用独立样本t检验进行评估。
结果
与无ARC的患者（n = 86）相比，有ARC的患者（n = 57）显示CAC的存在率显著更高（87.7%对24.4%；P < 0.001），且有CAC的患者平均CACS更高（700.6±941.2对256.4±724.3；P = 0.009）。计算得出ARCV>40 mm³的患者（n = 32）与ARCV<40 mm³的患者（n = 25）相比，严重CAC的发生率显著更高（56.3%对24.0%；P = 0.014）。与无CAC的患者（n = 42）相比，有CAC的患者（n = 101）显示ARC的存在率显著更高（83.3%对50.5%；P < 0.001）且平均ARCV更高（95.4±116.2mm³对29.7±33.0 mm³；P = 0.003）。与轻度至中度CAC的患者（n = 33，平均ARCV：61.9±64.8mm³）相比，严重CAC（n = 24）与平均ARCV增加（122.3±148.8mm³）相关（P < 0.05）。
结论
在冠状动脉DSCT血管造影期间的钙化积分扫描中，ARC的程度与CAC的存在及程度直接相关。
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