Apparent sequence preference in cleavage of linear B-DNA by the Cu(II):thiol system.
作者信息
John D C, Douglas K T
机构信息
Department of Pharmacy, University of Manchester, UK.
出版信息
Biochem Biophys Res Commun. 1989 Dec 29;165(3):1235-42. doi: 10.1016/0006-291x(89)92734-4.
PMID:2610689
Abstract
Cleavage of a linear tyr T fragment of duplex DNA by Cu(II):thiol combinations occurs with apparent sequence preference. The sequence selectivity was unaffected by the size, chirality or substitution pattern of the monothiol partner, presumably indicating that the Cu(II):RSH system is probing some local conformational/dynamic aspect of the DNA.
摘要
Zotero 插件