Yamada Yasuhiro, Okihara Koji, Iwata Tsuyoshi, Masui Koji, Kamoi Kazumi, Yamada Kei, Miki Tsuneharu
Department of Urology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Asian J Androl. 2015 Nov-Dec;17(6):899-903. doi: 10.4103/1008-682X.151391.
External beam radiotherapy (EBRT) is a standard treatment for prostate cancer. Despite the development of novel radiotherapy techniques such as intensity-modulated conformal radiotherapy, the risk of local recurrence after EBRT has not been obviated. Various local treatment options (including salvage prostatectomy, brachytherapy, cryotherapy, and high-intensity focused ultrasound [HIFU]) have been employed in cases of local recurrence after primary EBRT. Brachytherapy is the first-line treatment for low-risk and selected intermediate-risk prostate tumors. However, few studies have examined the use of brachytherapy to treat post-EBRT recurrent prostate cancer. The purpose of this paper is to analyze the current state of our knowledge about the effects of salvage brachytherapy in patients who develop locally recurrent prostate cancer after primary EBRT. This article also introduces our novel permanent brachytherapy salvage method.
外照射放疗（EBRT）是前列腺癌的标准治疗方法。尽管诸如调强适形放疗等新型放疗技术不断发展，但EBRT后局部复发的风险仍未消除。在初次EBRT后局部复发的病例中，已采用了各种局部治疗方案（包括挽救性前列腺切除术、近距离放射治疗、冷冻治疗和高强度聚焦超声[HIFU]）。近距离放射治疗是低风险和部分中风险前列腺肿瘤的一线治疗方法。然而，很少有研究探讨使用近距离放射治疗来治疗EBRT后复发性前列腺癌。本文的目的是分析我们目前对挽救性近距离放射治疗对初次EBRT后发生局部复发性前列腺癌患者的影响的了解情况。本文还介绍了我们新颖的永久性近距离放射治疗挽救方法。
