Marquet A, Thibaut S, LePabic E, Huon J F, Ballereau F
Centre ressource en antibiologie, hôpital Saint-Jacques, MedQual, CHU de Nantes, 85, rue Saint-Jacques, 44093 Nantes cedex 01, France.
Centre ressource en antibiologie, hôpital Saint-Jacques, MedQual, CHU de Nantes, 85, rue Saint-Jacques, 44093 Nantes cedex 01, France.
Med Mal Infect. 2015 Aug;45(8):313-7. doi: 10.1016/j.medmal.2015.05.006. Epub 2015 Jun 22.
We had for aim to assess antibiotic consumption and to better understand their use in nursing homes so as to target messages on relevant practice procedures sent to prescribers.
The MedQual network asked nursing homes with in-house pharmacies to participate in a retrospective collection of yearly antibiotic consumption data with an Excel(®) spread sheet according to the Health Ministry recommendations.
Fifty-two nursing homes participated in 2011, 2012, and 74 in 2013, accounting for 10% of the Pays de la Loire region's nursing homes and 15% of beds. The medians of total antibiotic consumption in daily-defined dose for 1000 patient-days were respectively 39 (32.4-49.0), 39.3 (34.4-52.9), and 44.8 (33.6-55.4). There was no significant difference between 2011 and 2013. Penicillins (J01C) were the most commonly used class with a median of 25.7 [IQ 18.8; 33.8] in 2011 and 30.4 [IQ 23.6; 41.3] in 2013. Quinolones (J01M) were the second most commonly used class with a median of 4.6 [IQ 2.9; 5.9] in 2011 and 3.8 [IQ 2.3; 6.5] in 2013, followed by the other beta-lactams (J01D) with a median of 2.5 [IQ 1.7; 4.5] in 2011 and 2,8 [IQ 1.7; 3.8] in 2013.
The monitoring of antibiotic consumption in nursing homes in the Pays de la Loire Region since 2011 has allowed identifying inappropriate use and helped improve practices. No increase of overall consumption was observed in nursing homes but the distribution according to antibiotic class changed. The current objective is to extend this monitoring and to send personalized messages to prescribers.
我们旨在评估抗生素的使用情况，并更好地了解其在养老院中的使用方式，以便针对向开处方者发送的有关相关操作规程的信息。
MedQual网络要求设有内部药房的养老院根据卫生部的建议，使用Excel（®）电子表格参与年度抗生素使用数据的回顾性收集。
2011年有52家养老院参与，2012年有74家，占卢瓦尔河地区养老院的10%和床位的15%。每1000个患者日按每日限定剂量计算的抗生素总使用量中位数分别为39（32.4 - 49.0）、39.3（34.4 - 52.9）和44.8（33.6 - 55.4）。2011年和2013年之间没有显著差异。青霉素（J01C）是最常用的类别，2011年中位数为25.7[四分位间距18.8；33.8]，2013年为30.4[四分位间距23.6；41.3]。喹诺酮类（J01M）是第二常用的类别，2011年中位数为4.6[四分位间距2.9；5.9]，2013年为3.8[四分位间距2.3；6.5]，其次是其他β-内酰胺类（J01D），2011年中位数为2.5[四分位间距1.7；4.5]，2013年为2.8[四分位间距1.7；3.8]。
自2011年以来对卢瓦尔河地区养老院抗生素使用情况的监测有助于识别不当使用并促进实践改进。养老院中未观察到总体使用量增加，但按抗生素类别划分的分布发生了变化。当前的目标是扩大这种监测，并向开处方者发送个性化信息。
