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巨细胞动脉炎的影像学检查

Imaging in Giant Cell Arteritis.

作者信息

Khan Asad, Dasgupta Bhaskar

机构信息

Department of Rheumatology, Southend University Hospital NHS Foundation Trust, Prittlewell Chase, Westcliff-on-Sea, Essex, SS0 0RY, UK.

出版信息

Curr Rheumatol Rep. 2015 Aug;17(8):52. doi: 10.1007/s11926-015-0527-y.

Abstract

Much progress has been made in the use of imaging as a diagnostic tool in giant cell arteritis (GCA), which assists in the management of patients where the initial diagnosis is unclear. This includes patients with atypical cranial symptoms, or with predominantly systemic, constitutional or limb symptoms. Ultrasound and magnetic resonance imaging are capable of visualising both the cranial and extracranial large vessel circulation, with vessel wall thickening and stenotic lesions being visualised. Computed tomographic angiography is helpful in visualising the aorta for aneurysm complicating GCA but can also detect vessel wall thickening in established large vessel vasculitis. PET-CT is a very sensitive test for early vascular inflammation in extracranial large vessel vasculitis, before aneurysmal or stenotic lesions have developed, of use in the patient with unexplained constitutional symptoms. The place of imaging in the follow-up of GCA is being investigated, and repeated imaging may be useful in select cases. Generally, vascular abnormalities become less defined once glucocorticoid treatment has been started, and therefore, imaging studies must be conducted early as part of a GCA fast-track assessment.

摘要

在将影像学作为巨细胞动脉炎(GCA)的诊断工具方面已取得了很大进展,这有助于对初始诊断不明确的患者进行管理。这包括有非典型颅脑症状的患者,或主要有全身、体质或肢体症状的患者。超声和磁共振成像能够显示颅内和颅外大血管循环,可看到血管壁增厚和狭窄病变。计算机断层血管造影有助于显示GCA并发动脉瘤时的主动脉情况,但也能检测已确诊的大血管血管炎中的血管壁增厚。正电子发射断层扫描-计算机断层扫描(PET-CT)对于颅外大血管血管炎在动脉瘤或狭窄病变出现之前的早期血管炎症是一种非常敏感的检测方法,适用于有不明原因体质症状的患者。影像学在GCA随访中的作用正在研究中,在某些情况下重复进行影像学检查可能有用。一般来说,一旦开始糖皮质激素治疗,血管异常就会变得不那么明显,因此,作为GCA快速评估的一部分,必须尽早进行影像学检查。

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