相似文献
1
Activation of IL-8 via PI3K/Akt-dependent pathway is involved in leptin-mediated epithelial-mesenchymal transition in human breast cancer cells.
Cancer Biol Ther. 2015;16(8):1220-30. doi: 10.1080/15384047.2015.1056409. Epub 2015 Jun 29.
2
Leptin promotes epithelial-mesenchymal transition of breast cancer via the upregulation of pyruvate kinase M2.
J Exp Clin Cancer Res. 2016 Oct 21;35(1):166. doi: 10.1186/s13046-016-0446-4.
3
Leptin induces functional activation of cyclooxygenase-2 through JAK2/STAT3, MAPK/ERK, and PI3K/AKT pathways in human endometrial cancer cells.
Cancer Sci. 2009 Mar;100(3):389-95. doi: 10.1111/j.1349-7006.2008.01053.x. Epub 2008 Dec 16.
4
Induction of metastatic potential by TrkB via activation of IL6/JAK2/STAT3 and PI3K/AKT signaling in breast cancer.
Oncotarget. 2015 Nov 24;6(37):40158-71. doi: 10.18632/oncotarget.5522.
5
WSTF promotes proliferation and invasion of lung cancer cells by inducing EMT via PI3K/Akt and IL-6/STAT3 signaling pathways.
Cell Signal. 2016 Nov;28(11):1673-82. doi: 10.1016/j.cellsig.2016.07.008. Epub 2016 Jul 21.
6
IL-7 splicing variant IL-7δ5 induces EMT and metastasis of human breast cancer cell lines MCF-7 and BT-20 through activation of PI3K/Akt pathway.
Histochem Cell Biol. 2014 Oct;142(4):401-10. doi: 10.1007/s00418-014-1222-1. Epub 2014 Apr 26.
7
[The effect of leptin and its mechanisms on the migration and invasion of human breast cancer MCF-7 cells].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2013 Dec;29(12):1272-6.
8
TSP50 facilitates breast cancer stem cell-like properties maintenance and epithelial-mesenchymal transition via PI3K p110α mediated activation of AKT signaling pathway.
J Exp Clin Cancer Res. 2024 Jul 20;43(1):201. doi: 10.1186/s13046-024-03118-4.
9
Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells.
Cancer Res. 2007 Mar 15;67(6):2497-507. doi: 10.1158/0008-5472.CAN-06-3075.
10
A-kinase-interacting protein 1 promotes EMT and metastasis via PI3K/Akt/IKKβ pathway in cervical cancer.
Cell Biochem Funct. 2020 Aug;38(6):782-791. doi: 10.1002/cbf.3547. Epub 2020 May 13.
引用本文的文献
1
The role of HOXA1 in cancer and targeted therapy.
Med Oncol. 2025 Aug 4;42(9):405. doi: 10.1007/s12032-025-02980-2.
2
A novel method of pancreatic islet transplantation at the liver surface using a gelatin hydrogel nonwoven fabric.
Cell Transplant. 2025 Jan-Dec;34:9636897251328419. doi: 10.1177/09636897251328419. Epub 2025 Apr 23.
3
The Regulation of Cellular Senescence in Cancer.
Biomolecules. 2025 Mar 20;15(3):448. doi: 10.3390/biom15030448.
4
The crosstalk between senescence, tumor, and immunity: molecular mechanism and therapeutic opportunities.
MedComm (2020). 2025 Jan 14;6(1):e70048. doi: 10.1002/mco2.70048. eCollection 2025 Jan.
5
The potential role of targeting the leptin receptor as a treatment for breast cancer in the context of hyperleptinemia: a literature review.
Naunyn Schmiedebergs Arch Pharmacol. 2025 Apr;398(4):3451-3466. doi: 10.1007/s00210-024-03592-9. Epub 2024 Nov 20.
6
Contents of exosomes derived from adipose tissue and their regulation on inflammation, tumors, and diabetes.
Front Endocrinol (Lausanne). 2024 Aug 16;15:1374715. doi: 10.3389/fendo.2024.1374715. eCollection 2024.
7
Exploring the multifaceted role of obesity in breast cancer progression.
Front Cell Dev Biol. 2024 Jul 8;12:1408844. doi: 10.3389/fcell.2024.1408844. eCollection 2024.
8
Impact of obesity on airway remodeling in asthma: pathophysiological insights and clinical implications.
Front Allergy. 2024 Mar 18;5:1365801. doi: 10.3389/falgy.2024.1365801. eCollection 2024.
9
A preliminary mechanistic exploration of the effect of leptin on the docetaxel sensitivity of MDA‑MB‑231 triple‑negative breast cancer cells.
Mol Clin Oncol. 2024 Feb 1;20(3):24. doi: 10.3892/mco.2024.2722. eCollection 2024 Mar.
10
Association of Four Interleukin-8 Polymorphisms (-251 A>T, +781 C>T, +1633 C>T, +2767 A>T) with Ovarian Cancer Risk: Focus on Menopausal Status and Endometriosis-Related Subtypes.
Biomedicines. 2024 Jan 30;12(2):321. doi: 10.3390/biomedicines12020321.
本文引用的文献
1
Leptin's Pro-Angiogenic Signature in Breast Cancer.
Cancers (Basel). 2013 Sep 6;5(3):1140-62. doi: 10.3390/cancers5031140.
2
Obesity and breast cancer: role of inflammation and aromatase.
J Mol Endocrinol. 2013 Nov 26;51(3):T51-9. doi: 10.1530/JME-13-0217. Print 2013 Dec.
3
Matrix metalloproteinase genes are associated with breast cancer risk and survival: the Breast Cancer Health Disparities Study.
PLoS One. 2013 May 16;8(5):e63165. doi: 10.1371/journal.pone.0063165. Print 2013.
4
Blockade of Autocrine TGF-β Signaling Inhibits Stem Cell Phenotype, Survival, and Metastasis of Murine Breast Cancer Cells.
J Stem Cell Res Ther. 2012 Feb 19;2(1):1-8. doi: 10.4172/2157-7633.1000116.
5
Relationship between the inflammatory molecular profile of breast carcinomas and distant metastasis development.
PLoS One. 2012;7(11):e49047. doi: 10.1371/journal.pone.0049047. Epub 2012 Nov 8.
6
Influence of IL-8 on the epithelial-mesenchymal transition and the tumor microenvironment.
Future Oncol. 2012 Jun;8(6):713-22. doi: 10.2217/fon.12.59.
7
Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells.
Biochim Biophys Acta. 2012 Apr;1825(2):207-22. doi: 10.1016/j.bbcan.2012.01.002. Epub 2012 Jan 24.
8
Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires β-catenin activation via Akt/GSK3- and MTA1/Wnt1 protein-dependent pathways.
J Biol Chem. 2012 Mar 9;287(11):8598-612. doi: 10.1074/jbc.M111.322800. Epub 2012 Jan 23.
9
Obesity and breast cancer: a clinical biochemistry perspective.
Clin Biochem. 2012 Feb;45(3):189-97. doi: 10.1016/j.clinbiochem.2011.11.016. Epub 2011 Dec 8.
10
Ob/ob serum promotes a mesenchymal cell phenotype in B16BL6 melanoma cells.
Clin Exp Metastasis. 2011 Dec;28(8):877-86. doi: 10.1007/s10585-011-9418-4. Epub 2011 Aug 31.
Zotero 插件