Obesity and breast cancer: a clinical biochemistry perspective.

OBJECTIVES

To evaluate the laboratory diagnosis aspects of obesity-related health problems with special reference to postmenopausal breast cancer.

DESIGN AND METHODS

We conducted a systemic search of the literature primarily from the PubMed to obtain the relevant data.

RESULTS

Obesity is associated with the dysregulations of a number of body components such as blood constituents, extracellular matrix, and hormones/growth factors axes, which could be utilized for early diagnosis.

CONCLUSIONS

Obesity-related disorders including breast cancer have emerged as major health problems in almost all the nations. There is a need to elucidate different biochemical markers that are being used in the clinics or have the potential for such use. A precise understanding of the complex pathologies related with obesity is useful in prevention, early diagnosis and overall clinical management.