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Proteostasis control by the unfolded protein response.
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Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases.
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Inhibition of the UFD-1-NPL-4 complex triggers an aberrant immune response in .
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Metformin modulates the unfolded protein responses, altering lifespan and health-promoting effects in UPR-activated worms.
PLoS One. 2025 Jun 16;20(6):e0326100. doi: 10.1371/journal.pone.0326100. eCollection 2025.
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PTPN2 inhibits TG-induced ERS-initiated TNBC apoptosis through the mitochondrial pathway.
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Mitochondrial unfolded protein response (UPR) as novel therapeutic targets for neurological disorders.
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Astragaloside IV as a promising therapeutic agent for liver diseases: current landscape and future perspectives.
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RNA metabolism: putting the brake on the UPR.
EMBO Rep. 2015 May;16(5):545-6. doi: 10.15252/embr.201540227. Epub 2015 Mar 25.
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The unfolded protein response is shaped by the NMD pathway.
EMBO Rep. 2015 May;16(5):599-609. doi: 10.15252/embr.201439696. Epub 2015 Mar 25.
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Rheb Inhibits Protein Synthesis by Activating the PERK-eIF2α Signaling Cascade.
Cell Rep. 2015 Feb 10;10(5):684-693. doi: 10.1016/j.celrep.2015.01.014. Epub 2015 Feb 7.
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The genetic architecture of the genome-wide transcriptional response to ER stress in the mouse.
PLoS Genet. 2015 Feb 4;11(2):e1004924. doi: 10.1371/journal.pgen.1004924. eCollection 2015 Feb.
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Ire1 has distinct catalytic mechanisms for XBP1/HAC1 splicing and RIDD.
Cell Rep. 2014 Nov 6;9(3):850-8. doi: 10.1016/j.celrep.2014.09.016. Epub 2014 Oct 30.
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RTCB-1 mediates neuroprotection via XBP-1 mRNA splicing in the unfolded protein response pathway.
J Neurosci. 2014 Nov 26;34(48):16076-85. doi: 10.1523/JNEUROSCI.1945-14.2014.
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TBL2 is a novel PERK-binding protein that modulates stress-signaling and cell survival during endoplasmic reticulum stress.
PLoS One. 2014 Nov 13;9(11):e112761. doi: 10.1371/journal.pone.0112761. eCollection 2014.

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