Hodes R M, Seyoum B
East Afr Med J. 1989 Dec;66(12):812-8.
Two hundred and forty available charts of medical patients treated for tuberculosis at Tikur Anbessa Hospital in Addis Ababa, Ethiopia over 2 years (9/83-9/85 were studied. TB was diagnosed in 11.2% of medical admissions. The average age of TB patients was 30.5; 58% were males; 53% were classed as poor. TB patients were poorer than other medical patients and averaged 38.9 days in hospital, non-TB patients averaged 31.9 days. Pulmonary disease was most common (47% of total), followed by spondylitis (12.1%), peritonitis (11.5%), and disseminated disease (11.1%). There were no cases of renal or cutaneous disease. 6% of admissions were diabetic, 16.4% had defaulted from previous TB treatment. Only 45% of patients had the diagnosis proven by histology or bacteriology. Pleural biopsy, lymph node biopsy, peritoneal biopsy, and sputum AFB stain were the most useful procedures in proving the diagnosis. A variety of drugs were given, 53% received INH-EMB-SM, 26% INH-SM-Thiacetazone; 32% received no form of vitamin supplements. The overall death rate was 8%, including 9% of pulmonary cases and 22% of patients with disseminated disease. Comparison is made with Ethiopian and other African data. It is suggested that patients receive definitive diagnostic tests earlier, along with earlier therapy and more consistent use of pyridoxine.
对埃塞俄比亚亚的斯亚贝巴提库尔安贝萨医院两年间(1983年9月至1985年9月)收治的240例结核病患者的病历进行了研究。在所有内科住院患者中,结核病的诊断率为11.2%。结核病患者的平均年龄为30.5岁;58%为男性;53%被归类为贫困人口。结核病患者比其他内科患者更贫困,住院平均天数为38.9天,非结核病患者平均住院天数为31.9天。肺部疾病最为常见(占总数的47%),其次是脊柱炎(12.1%)、腹膜炎(11.5%)和播散性疾病(11.1%)。没有肾或皮肤疾病的病例。6%的入院患者患有糖尿病,16.4%的患者此前曾中断结核病治疗。只有45%的患者经组织学或细菌学确诊。胸膜活检、淋巴结活检、腹膜活检和痰抗酸杆菌染色是确诊最有用的检查方法。使用了多种药物,53%的患者接受异烟肼-乙胺丁醇-链霉素治疗,26%接受异烟肼-链霉素-氨硫脲治疗;32%的患者未接受任何形式的维生素补充剂。总死亡率为8%,其中肺部病例死亡率为9%,播散性疾病患者死亡率为22%。并与埃塞俄比亚和其他非洲的数据进行了比较。建议患者更早接受确定性诊断检查,同时更早开始治疗并更持续地使用吡哆醇。