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鹦鹉热衣原体羊流产株主要外膜蛋白基因的序列分析

Sequence analysis of the major outer membrane protein gene of an ovine abortion strain of Chlamydia psittaci.

作者信息

Herring A J, Tan T W, Baxter S, Inglis N F, Dunbar S

机构信息

Moredun Research Institute, Edinburgh, U.K.

出版信息

FEMS Microbiol Lett. 1989 Nov;53(1-2):153-8. doi: 10.1016/0378-1097(89)90383-2.

DOI:10.1016/0378-1097(89)90383-2
PMID:2612883
Abstract

The major outer membrane protein (MOMP) gene from an ovine abortion strain of Chlamydia psittaci (S26/3) has been cloned and sequenced. The gene shows the features of other chlamydial MOMPs but comparison with the previously reported sequence for the ovine abortion isolate A22/M has revealed substantial sequence divergence which is clustered into the same four intramolecular regions as the sequence variation found between C. trachomatis serovars. Subsequent restriction enzyme analysis of A22/M DNA has shown that it has an avian-type genomic profile and thus the comparison is between types rather than between strains.

摘要

鹦鹉热衣原体羊流产株(S26/3)的主要外膜蛋白(MOMP)基因已被克隆并测序。该基因具有其他衣原体MOMP的特征,但与先前报道的羊流产分离株A22/M的序列比较显示,存在大量序列差异,这些差异集中在与沙眼衣原体血清型之间发现的序列变异相同的四个分子内区域。随后对A22/M DNA进行的限制性酶切分析表明,它具有禽型基因组图谱,因此这种比较是在不同类型之间而非菌株之间进行的。

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