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巴西戊型肝炎病毒感染:1998年至2013年基于实验室监测的结果

Hepatitis E virus infection in Brazil: results of laboratory-based surveillance from 1998 to 2013.

作者信息

Passos-Castilho Ana Maria, de Sena Anne, Reinaldo Mônica Renata, Granato Celso Francisco Hernandes

机构信息

Departamento de Medicina, Universidade Federal de São Paulo, São Paulo, BR.

出版信息

Rev Soc Bras Med Trop. 2015 Jul-Aug;48(4):468-70. doi: 10.1590/0037-8682-0036-2015. Epub 2015 Jun 26.

Abstract

INTRODUCTION

Data on hepatitis E virus (HEV) in Brazil are limited. We analyzed 15 years of HEV surveillance data in a major clinical laboratory in São Paulo, Brazil.

METHODS

The seroprevalence of HEV of 2,271 patients subjected to anti-HEV tests from 1998 to 2013 were analyzed.

RESULTS

HEV seroprevalence was 2.1%, and the anti-HEV IgM positivity rate was 4.9%. Six hepatitis E patients were identified.

CONCLUSIONS

HEV seroprevalence and detection rates appear to have increased in recent years. Hepatitis E should be investigated further and included in the differential diagnosis of hepatitis in Brazil.

摘要

引言

巴西戊型肝炎病毒(HEV)的数据有限。我们分析了巴西圣保罗一家主要临床实验室15年的戊型肝炎病毒监测数据。

方法

分析了1998年至2013年接受抗HEV检测的2271例患者的戊型肝炎病毒血清流行率。

结果

戊型肝炎病毒血清流行率为2.1%,抗HEV IgM阳性率为4.9%。确诊了6例戊型肝炎患者。

结论

近年来,戊型肝炎病毒血清流行率和检出率似乎有所上升。在巴西,戊型肝炎应进一步调查,并纳入肝炎的鉴别诊断。

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