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左心发育不全综合征的自然病史。

The natural history of the hypoplastic left heart syndrome.

作者信息

Allan L D, Sharland G, Tynan M J

机构信息

Department of Perinatal, Guy's Hospital, London, U.K.

出版信息

Int J Cardiol. 1989 Dec;25(3):341-3. doi: 10.1016/0167-5273(89)90226-x.

DOI:10.1016/0167-5273(89)90226-x
PMID:2613383
Abstract

In a fetus, examined initially at 22 weeks gestation, we identified the echocardiographic features of a dilated, hypertrophied and poorly contracting left ventricle. The presumptive diagnosis was critical aortic stenosis. Subsequent scans at 32 weeks and at term showed that the left ventricle had not grown since the first study such that the left ventricle had developed the appearance of a hypoplastic and densely echogenic chamber. Thus, in some forms of the hypoplastic left heart syndrome, the left ventricle can be of normal size or even dilated in early pregnancy. This may mean that the more subtle sign of poor left ventricular contraction could be overlooked in a routine four-chamber view obstetric scan.

摘要

在一名最初于妊娠22周时接受检查的胎儿中,我们识别出左心室扩张、肥厚且收缩功能不佳的超声心动图特征。初步诊断为严重主动脉瓣狭窄。随后在32周和足月时进行的扫描显示,自首次检查以来左心室没有生长,以至于左心室呈现出发育不全且回声密集的腔室外观。因此,在某些类型的左心发育不全综合征中,左心室在妊娠早期可能大小正常甚至扩张。这可能意味着在常规的产科四腔心切面扫描中,左心室收缩功能不佳这一更为细微的征象可能会被忽略。

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