Zwiauer K, Schmidinger H, Klicpera M, Mayr H, Widhalm K
Department of Pediatrics, University Vienna, Austria.
Int J Obes. 1989;13 Suppl 2:101-5.
Twenty-four hour electrographic recordings were made on 36 grossly obese children and adolescents during a 3-week weight reduction regimen with a 525 kcal (2196 kj) mixed diet at weekly intervals. One hundred and ten Holter ECGs were analysed. Weight loss during the treatment was calculated to be 5.7 +/- 1.6 kg. Average and minimal heart rate decreased constantly throughout the study period from 83.9 +/- 9 to 75 +/- 9/min and 53 +/- 6 to 45 +/- 6/min, respectively (P less than 0.01, P less than 0.005). During the second week maximal heart rate increased significantly but returned to baseline values in the third week. Neither before nor during the period of therapy were any dysrhythmias monitored. Dietary regimens containing 500-700 kcal, based on a mixed composition of foods with sufficient amounts of minerals, can be regarded as a safe therapeutic tool in the treatment of obese children and adolescents.
在为期3周的减重方案中，对36名严重肥胖的儿童和青少年每隔一周进行24小时心电图记录，饮食为525千卡（2196千焦）的混合饮食。分析了110份动态心电图。治疗期间体重减轻计算为5.7±1.6千克。在整个研究期间，平均心率和最低心率持续下降，分别从83.9±9次/分钟降至75±9次/分钟，从53±6次/分钟降至45±6次/分钟（P<0.01，P<0.005）。在第二周，最高心率显著增加，但在第三周恢复到基线值。在治疗前和治疗期间均未监测到任何心律失常。含有500-700千卡、由矿物质含量充足的混合食物组成的饮食方案，可被视为治疗肥胖儿童和青少年的安全治疗工具。
