Nagaraja D, Taly A B, Rao B S
J Assoc Physicians India. 1989 Apr;37(4):253-4.
One hundred patients with ischaemic cerebro vascular disease (TIA/RIND--67% and completed stroke--33%) were evaluated for various clinical and biochemical risk factors. Evidence of extra-cranial carotid vascular disease (ECCVD) was looked for by using Doppler scan and carotid angiography. Of the 28 patients with abnormal Dop scan, 27 were confirmed to have ECCVD by angiography. Though the history of hypertension was elicited in 40%, only 28% had BP of 160/95 mm Hg or more during hospital stay. Hypertension was twice more common in ECCVD group compared to the group with normal carotid vessels. Obesity was seen in 15%, diabetes mellitus in 10% and 1% had hyperuricaemia. Total cholesterol was elevated in 29% and HDL cholesterol fraction was decreased (less than 35 mg%) in 43%. The reduction of HDL cholesterol was more frequent in ECCVD group (63%) and in hypertensive (73%) patients. Lipoproteins, triglycerides, free fatty acids and phospholipids were not significantly affected.
对100例缺血性脑血管疾病患者（短暂性脑缺血发作/可逆性缺血性神经功能缺损占67%，完全性卒中占33%）进行了各种临床和生化危险因素评估。通过多普勒扫描和颈动脉血管造影检查颅外颈动脉血管疾病（ECCVD）证据。在28例多普勒扫描异常的患者中，27例经血管造影证实患有ECCVD。虽然40%的患者有高血压病史，但住院期间只有28%的患者血压达到160/95 mmHg或更高。与颈动脉血管正常的组相比，ECCVD组高血压的发生率高出两倍。15%的患者肥胖，10%的患者患有糖尿病，1%的患者有高尿酸血症。29%的患者总胆固醇升高，43%的患者高密度脂蛋白胆固醇水平降低（低于35mg%）。ECCVD组（63%）和高血压患者（73%）中高密度脂蛋白胆固醇降低更为常见。脂蛋白、甘油三酯、游离脂肪酸和磷脂未受到显著影响。
