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评估IV类激光疗法对非体外循环冠状动脉搭桥手术患者术后疼痛缓解的可行性和疗效:一项初步研究。

Assessment of feasibility and efficacy of Class IV laser therapy for postoperative pain relief in off-pump coronary artery bypass surgery patients: A pilot study.

作者信息

Karlekar Anil, Bharati Saswata, Saxena Ravindra, Mehta Kanchan

机构信息

Department of Anaesthesiology and Critical Care, Fortis Escorts Heart Institute, New Delhi, India.

出版信息

Ann Card Anaesth. 2015 Jul-Sep;18(3):317-22. doi: 10.4103/0971-9784.159800.

Abstract

BACKGROUND

Laser therapy, for its established analgesic properties with minimal side effects, has been used for the treatment of chronic pain. However, it has not been used for the treatment of acute postoperative pain. This pilot study was designed to assess the feasibility and efficacy of Class IV laser on postoperative pain relief following off-pump coronary artery bypass graft (OPCABG) surgery, as a component of multimodal analgesia (MMA) technique.

METHODS

This open observational prospective study comprised of 100 adult patients (84 male, 16 female) who underwent OPCABG through sternotomy. For postoperative analgesia, they were subjected to laser therapy subjected to laser therapy in addition to the standard institutional pain management protocol comprising of IV infusion/bolus of tramadol and paracetamol and fentanyl bolus as rescue analgesic. Pain intensity was measured by Verbal Rating Scale (VRS). The laser therapy was scheduled as once a day regime for three consecutive postoperative days (PODs) starting on POD 1, 30 min following tracheal extubation. The subsequent laser applications were also scheduled at the same time of the day as on day 1 if VRS was ≥5. 10 W Class IV laser was applied over 150 cm² sternal wound area for 150 s. VRS was used to assess pain severity and was recorded for statistical analysis using Friedman Test.

RESULTS

The mean (standard deviation [SD]) VRS of all the 100 patients just before application of the first dose of laser was 7.31 (0.94) while on MMT; the same fell to 4.0 (1.279) and 3.40 (2.697) at 1 h and 24 h respectively following first dose of laser. The change of VRS over first 24 h among all the 100 patients was statistically significant (P = 0.000). Laser was re-applied in 40 patients whose VRS was ≥5 (mean [SD] - 6.38 [0.868]) at 24th h. After receiving the 2nd dose of laser the VRS scores fell significantly (P = 0.000) and became 0 at 54th h. No patients required 3rd dose of the laser. No patient required rescue analgesic while on laser therapy.

CONCLUSION

Class IV laser can be an effective technique for postoperative analgesia following OPCABG surgery through sternotomy when included as a component of MMA technique.

摘要

背景

激光疗法因其已证实的镇痛特性且副作用极小,已被用于治疗慢性疼痛。然而,它尚未用于治疗急性术后疼痛。本前瞻性初步研究旨在评估作为多模式镇痛(MMA)技术一部分的IV类激光对非体外循环冠状动脉搭桥术(OPCABG)术后疼痛缓解的可行性和疗效。

方法

这项开放性观察性前瞻性研究纳入了100例成年患者(84例男性,16例女性),他们通过胸骨切开术接受了OPCABG手术。术后镇痛方面,除了标准的机构疼痛管理方案(包括静脉输注/推注曲马多和对乙酰氨基酚以及推注芬太尼作为急救镇痛药)外,他们还接受了激光治疗。疼痛强度通过视觉模拟评分法(VRS)进行测量。激光治疗计划在术后第1天开始,连续3天每天进行一次,在气管拔管后30分钟进行。如果VRS≥5,后续的激光治疗也安排在与第1天相同的时间。将10W的IV类激光照射在150cm²的胸骨伤口区域,持续150秒。使用VRS评估疼痛严重程度,并记录数据用于采用Friedman检验进行统计分析。

结果

在首次应用激光前,所有100例患者的平均(标准差[SD])VRS为7.31(0.94),而在首次激光治疗后1小时和24小时,VRS分别降至4.0(1.279)和3.40(2.697)。所有100例患者在最初24小时内VRS的变化具有统计学意义(P = 0.000)。在第24小时,40例VRS≥5(平均[SD] - 6.38 [0.868])的患者再次接受了激光治疗。接受第二剂激光治疗后,VRS评分显著下降(P = 0.000),并在第54小时降至0。没有患者需要第三剂激光治疗。在接受激光治疗期间,没有患者需要急救镇痛药。

结论

当作为MMA技术的一部分时,IV类激光可以成为通过胸骨切开术进行OPCABG术后镇痛的有效技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/569e/4881709/e53a887fde6e/ACA-18-317-g001.jpg

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