Ezzati Kamran, Fekrazad Reza, Raoufi Zeinab
Neuroscience Research Center, Poorsina Hospital, Faculty of medicine, Guilan University of Medical Sciences, Rasht, Iran.
Department of Periodontology, Dental Faculty - Laser Research Center in Medical Sciences, AJA University of Medical Sciences, Tehran, Iran.
J Lasers Med Sci. 2019 Spring;10(2):79-85. doi: 10.15171/jlms.2019.13. Epub 2019 Feb 25.
One of the major complains after surgery is pain. Recent advances in the prevention and reduction of postoperative pain have provided several modalities. One of them is the use of laser irradiation on the surgical area. To evaluate the effects of low level laser therapy (LLLT) on pain and side effects after surgery. In this research, databases such as: PubMed, Science Direct, Google Scholar, Springer and Cochrane were used and the words of laser therapy, photobiomodulation, therapeutic laser, low level laser therapy, surgery and pain were searched. Articles, including systematic reviews, original articles, case series, and clinical intervention studies related to these words, were studied. The language of all articles was English and consists of papers from 2009 until 2017. A total of 370 papers were studied and 10 articles that met inclusion criteria were selected for this review. Few of these articles were followed up. Surgery included a wide range of surgeries including mastectomy, breast augment post-fracture, episiotomy, tonsillectomy and hernia. The methodological quality score on the PEDro scale was between 5 and 11. 8 trials reported positive effects and 2 trials reported negative effects. In order to study clinical effect size of laser therapy after surgery, only 4 papers met entry criteria and the mean effect sizes were 0.13 to 2.77. Accordingly, the best treatment protocol included a red laser dose of 4 J/cm for the post-operative pain of tonsillectomy, which was irradiated through the infra mandibular angle on the tonsils. LLLT may be an appropriate modality for reducing pain after surgery, nevertheless the effect size of this modality is variable. Therefore, further research based on proper protocols for these patients and follow-up of therapeutic course should be designed and implemented.
术后的主要抱怨之一是疼痛。在预防和减轻术后疼痛方面的最新进展提供了多种方式。其中之一是在手术区域使用激光照射。为了评估低强度激光疗法(LLLT)对术后疼痛和副作用的影响。在本研究中,使用了诸如PubMed、ScienceDirect、谷歌学术、Springer和Cochrane等数据库,并搜索了激光疗法、光生物调节、治疗性激光、低强度激光疗法、手术和疼痛等词汇。研究了与这些词汇相关的文章,包括系统评价、原创文章、病例系列和临床干预研究。所有文章的语言均为英语,涵盖2009年至2017年的论文。共研究了370篇论文,选择了10篇符合纳入标准的文章进行本综述。这些文章中很少有进行随访的。手术包括广泛的手术类型,如乳房切除术、骨折后隆胸、会阴切开术、扁桃体切除术和疝气手术。在PEDro量表上的方法学质量评分在5至11之间。8项试验报告了积极效果,2项试验报告了消极效果。为了研究手术后激光疗法的临床效应大小,只有4篇论文符合入选标准,平均效应大小为0.13至2.77。因此,最佳治疗方案包括对于扁桃体切除术后疼痛采用4 J/cm的红色激光剂量,通过下颌角照射扁桃体。低强度激光疗法可能是减轻术后疼痛的一种合适方式,然而这种方式的效应大小是可变的。因此,应设计并实施基于针对这些患者的适当方案以及治疗过程随访的进一步研究。