Stiel G M, Stiel L S, Donath K, Schofer J, Haaker P, Klotz E, Koppe R, Linde R, Mathey D G
Department of Cardiology, University Hospital Eppendorf, Hamburg, FRG.
Int J Card Imaging. 1989;5(1):53-61. doi: 10.1007/BF01745232.
Digital Flashing Tomosynthesis (DFTS) represents a technique for three-dimensional (3D) coronary angiography. Four ECG-gated simultaneously flashed X-ray tubes generate a multiperspective digital substraction image as DFTS multiangiogram for 3D reconstruction and visualization. Computerized morphologic and morphometric quantitative analysis can be performed including videodensitometry. Postmortem coronary angiography of 30 human hearts with suspected coronary artery disease was performed by 35-mm cine technique and by DFTS. The results of angiographic measurements in 50 stenotic arterial segments were compared with the histologic reference and show excellent regression results with correlation coefficients of more than 0.95 (p less than or equal to 0.0001). No significant differences in standard errors of estimates between the techniques were found. DFTS yields an accuracy in depiction of the coronary arteries and angiographic estimation of arterial lumen equivalent to 35-mm cineangiography. DFTS images can be directly used for visual interpretation and for computerized morphologic and morphometric quantitative analysis. DFTS technology reduces the amount of radiation exposure, the amount of contrast medium, and the time of the procedure. DFTS offers the possibility to obtain 3D images of the coronary artery tree.
数字闪烁断层合成（DFTS）是一种用于三维（3D）冠状动脉造影的技术。四个心电图门控的同步闪烁X射线管生成多视角数字减影图像，作为用于3D重建和可视化的DFTS多血管造影图。可以进行包括视频密度测定在内的计算机形态学和形态计量学定量分析。采用35毫米电影技术和DFTS对30颗疑似冠心病的人体心脏进行了死后冠状动脉造影。对50个狭窄动脉节段的血管造影测量结果与组织学参考进行了比较，结果显示相关性极佳，相关系数超过0.95（p≤0.0001）。两种技术在估计标准误差方面未发现显著差异。DFTS在冠状动脉描绘和动脉腔血管造影估计方面的准确性与35毫米电影血管造影相当。DFTS图像可直接用于视觉解读以及计算机形态学和形态计量学定量分析。DFTS技术减少了辐射暴露量、造影剂用量以及检查时间。DFTS提供了获取冠状动脉树3D图像的可能性。
