Mulder G D, Walker A
Surgery Department, Veterans Administration Hospital, Denver, Colorado.
J R Soc Med. 1989 Dec;82(12):739-40. doi: 10.1177/014107688908201213.
Four patients with five wounds were randomly assigned to treatment with three occlusive dressings: DuoDERM, Restore and Comfeel Ulcus; the dressings were left intact for 24-48 h. When the dressings were removed, it was found that wounds that had been covered with Restore and Comfeel contained coagulated sanguinous material. Two wounds that had been covered with Comfeel and Restore, respectively, were then covered with DuoDERM, while one wound previously covered with DuoDERM was covered with Restore. Either no clotting occurred under DuoDERM or clots may have resolved. Although these preliminary data suggest that DuoDERM gel may have fibrinolytic properties, more extensive and controlled studies are needed to assess the characteristics of this dressing.
4名患者共5处伤口被随机分配使用3种封闭性敷料进行治疗：多爱肤（DuoDERM）、瑞速愈（Restore）和康惠尔溃疡贴（Comfeel Ulcus）；敷料完整保留24 - 48小时。去除敷料时发现，使用瑞速愈和康惠尔溃疡贴覆盖的伤口含有凝固的血性物质。然后，分别用多爱肤覆盖了2处先前用康惠尔溃疡贴和瑞速愈覆盖的伤口，同时，将1处先前用多爱肤覆盖的伤口改用瑞速愈覆盖。在多爱肤覆盖下要么没有发生凝血，要么血块可能已经溶解。尽管这些初步数据表明多爱肤凝胶可能具有纤维蛋白溶解特性，但需要更广泛且可控的研究来评估这种敷料的特性。
