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[血浆游离氨基酸分布模式的统计学研究]

[A statistical study on distribution patterns of plasma free amino acids].

作者信息

Yonezawa S, Ohno Y, Imai M, Futohashi M

出版信息

Rinsho Byori. 1989 Dec;37(12):1373-8.

PMID:2614967
Abstract

We investigated the distribution patterns of 23 plasma free amino acids in 875 healthy adults (375 males and 500 females, aged from 30 to 50 years), which were obtained after an overnight fast, using three statistical parameters of MLL (Maximum Logarithmic Likelihood), square root of b1, b2, and selected their patterns from the three of ordinary normal, log-normal and square root-normal distributions. The distribution patterns of the majority of plasma free amino acids were found to be either log-normal or square root-normal, and occasionally ordinary normal. We also evaluated the reliability of our selection system by a simulation model of 100 sets of values for plasma free amino acids that were randomly determined by the parameters of original data. Good reliability was observed for some amino acids. Our selection system may be useful for comparing the present results with the future results that will be obtained by other methods.

摘要

我们研究了875名健康成年人(375名男性和500名女性,年龄在30至50岁之间)在禁食过夜后血浆中23种游离氨基酸的分布模式,使用了最大对数似然(MLL)、b1的平方根、b2这三个统计参数,并从普通正态分布、对数正态分布和平方根正态分布这三种分布中选择它们的模式。发现大多数血浆游离氨基酸的分布模式为对数正态或平方根正态,偶尔为普通正态。我们还通过一个模拟模型评估了我们选择系统的可靠性,该模型使用原始数据参数随机确定100组血浆游离氨基酸值。观察到某些氨基酸具有良好的可靠性。我们的选择系统可能有助于将当前结果与未来通过其他方法获得的结果进行比较。

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