Töz Emrah, Kurt Sefa, Canda Mehmet Tunç, Şahin Çağdaş, Uyar Ibrahim
Emrah Töz, Tepecik Training and Research Hospital, Department of Obstetrics and Gynecology, Izmir 35170, Turkey.
Sefa Kurt, Department of Obstetrics and Gynecology, Izmir Dokuz Eylül University, Izmir, Turkey.
Pak J Med Sci. 2015;31(3):654-7. doi: 10.12669/pjms.313.6934.
To compare the frequency of asymptomatic microhematuria (AMH) in patients with stage 2-4 and stage 0-1 pelvic organ prolapse (POP).
The hospital database was searched for women diagnosed with pelvic floor disorders and all medical records were reviewed retrospectively for the presence of AMH. An additional search was conducted for women with other benign gynecological conditions such as myoma uteri, endometrial hyperplasia or adnexal masses without evidence of pelvic organ prolapse (control group). The control group was created using 1:1 matching for age and menopausal status. The frequency of AMH in these patients were compared. The degree of hematuria was categorized as reported by the laboratory as 3 to 25 (low grade hematuria), 26 to 50 (intermediate grade hematuria) and 51 or more (high grade hematuria) red blood cell/high powered field.
AMH is statistically significant more often seen in study group than in control group (p:0.016). In the prolapse group 20 women (13.7%) had AMH compared with 9 (6.2%) in the control group. All of 29 patients with AMH had low grade hematuria defined as < 25 red blood cell/high powered field. Patients were followed up for 22 ± 7 (12 to 33) months. No bladder cancer and no cancer of the upper urinary tract has been detected in these 29 patients with AMH during follow-up.
Women with stage 2-4 POP are more likely to be diagnosed with AMH than those with stage 0-1 prolapse.
比较2 - 4期和0 - 1期盆腔器官脱垂（POP）患者无症状性微血尿（AMH）的发生率。
检索医院数据库中诊断为盆底疾病的女性患者，并对所有病历进行回顾性审查以确定是否存在AMH。另外检索了患有其他良性妇科疾病（如子宫肌瘤、子宫内膜增生或附件包块）且无盆腔器官脱垂证据的女性患者（对照组）。对照组采用年龄和绝经状态1:1匹配创建。比较这些患者中AMH的发生率。血尿程度根据实验室报告分为3至25（低级别血尿）、26至50（中级别血尿）和51或更多（高级别血尿）个红细胞/高倍视野。
研究组中AMH的发生率在统计学上显著高于对照组（p:0.016）。脱垂组中有20名女性（13.7%）患有AMH，而对照组中有9名（6.2%）。29例AMH患者均为低级别血尿，定义为<25个红细胞/高倍视野。患者随访22±7（12至33）个月。在这29例AMH患者的随访期间，未检测到膀胱癌和上尿路癌。
2 - 4期POP女性比0 - 1期脱垂女性更有可能被诊断为AMH。
