Ekin A, Gezer C, Taner C E, Ozeren M, Avci M E, Ciftci S, Dogan A, Gezer N S
Clin Exp Obstet Gynecol. 2015;42(3):327-30.
The authors' aim was to detect the associated anomalies and their effect on the management of the fetuses with omphalocele and gastroschisis. Between the period of 2007-2013, the data of fetuses with abdominal wall defects were analyzed. Chromosomal abnormalities and associated morphologic anomalies diagnosed by ultrasonography and autopsy were evaluated. Of the. 61 fetuses, ten (20.4%) omphalocele cases and nine (75%) gastroschisis cases were isolated. Chromosomal abnormalities were found in seven fetuses with omphalocele cases. All fetuses with abnormal karyotypes had multiple additional anomalies. Termination rate was 65.3% for omphalocele group versus none in the gastroschisis group. To give better counseling about the prognosis and outcome of the fetuses with abdominal wall defects, detection of additional anomalies as well as type of the defect are essential tools even if the karyotype is normal.
作者的目的是检测合并的异常情况及其对腹裂和脐膨出胎儿治疗的影响。在2007年至2013年期间，对腹壁缺陷胎儿的数据进行了分析。评估了通过超声检查和尸检诊断出的染色体异常和相关形态学异常。在61例胎儿中，10例（20.4%）脐膨出病例和9例（75%）腹裂病例为孤立性病例。在脐膨出病例的7例胎儿中发现了染色体异常。所有核型异常的胎儿都有多种其他异常。脐膨出组的终止妊娠率为65.3%，而腹裂组则无终止妊娠情况。为了更好地为腹壁缺陷胎儿的预后和结局提供咨询，即使核型正常，检测其他异常以及缺陷类型也是至关重要的工具。
