Kawalec Paweł P, Malinowski Krzysztof P
Departament of Drug Management, Institute of Public Health, Faculty of Health Sciences, Jagiellonian University Medical College, 20 Grzegorzecka, 31-531 Kraków, Poland.
Expert Rev Pharmacoecon Outcomes Res. 2015;15(4):667-73. doi: 10.1586/14737167.2015.1065733. Epub 2015 Jul 7.
Systemic lupus erythematosus, systemic sclerosis and sarcoidosis are three different autoimmune systemic diseases that generate a significant burden to society due to treatment costs and also those caused by a work disability or absenteeism among patients. Relevant 2012 data referring to the three components of absenteeism produced by autoimmune systemic diseases, sick leave, short-term and long-term work disability, were obtained from the Social Insurance Institution in Poland (PSII). By applying the Human Capital Approach using gross domestic product per capita, gross value added per worker and gross income per worker in 2012, total indirect costs for the diseases were calculated. All costs were presented in euros and were valid for 2012. The PSII recorded 1600 patients with systemic lupus erythematosus, 500 patients with systemic sclerosis and 2700 patients with sarcoidosis in the 2012 - total indirect costs were as high as 7,260,595, 2,268,571 and 4,027,575 EUR, respectively. Costs were estimated using gross domestic product per capita; 17,485,412, 5,463,312 and 9,699,455 EUR, accordingly, calculated using gross value added per worker and 5,346,933, 1,670,648 and 2,966,034 EUR estimated using gross income per worker, respectively. Considering only data on absenteeism gathered by the PSII we can conclude that the three autoimmune systemic diseases bore great indirect costs. Their social burden for Poland could be even greater when considering presenteeism as well as other components of absenteeism such as loss of unpaid work, a gray economy or loss of leisure time.
系统性红斑狼疮、系统性硬化症和结节病是三种不同的自身免疫性全身性疾病,由于治疗费用以及患者工作残疾或缺勤所造成的费用,给社会带来了巨大负担。2012年有关自身免疫性全身性疾病导致的缺勤三个组成部分(病假、短期和长期工作残疾)的相关数据,是从波兰社会保险机构(PSII)获取的。通过采用人力资本方法,利用2012年人均国内生产总值、每名工人的增加值总额和每名工人的总收入,计算出了这些疾病的总间接成本。所有成本均以欧元表示,且适用于2012年。PSII记录显示,2012年有1600例系统性红斑狼疮患者、500例系统性硬化症患者和2700例结节病患者,总间接成本分别高达7260595欧元、2268571欧元和4027575欧元。相应地,使用人均国内生产总值估算的成本分别为17485412欧元、5463312欧元和9699455欧元;使用每名工人增加值总额计算的成本分别为5346933欧元、1670648欧元和2966034欧元;使用每名工人总收入估算的成本分别为5346933欧元、1670648欧元和2966034欧元。仅考虑PSII收集的缺勤数据,我们可以得出结论,这三种自身免疫性全身性疾病承担了巨大的间接成本。如果考虑到出勤主义以及缺勤的其他组成部分,如无薪工作损失、灰色经济或休闲时间损失,它们给波兰带来的社会负担可能会更大。