Chaudhary Satyarth, Noor Mohd Talha, Jain Sunil, Kumar Ravindra, Thakur Bhagwan Singh
Department of Gastroenterology, Sri Aurobindo Medical College and P.G. Institute, Indore, Madhya Pradesh, India.
Department of Gastroenterology, Sri Aurobindo Medical College and P.G. Institute, Indore, Madhya Pradesh, India
Trop Doct. 2016 Jan;46(1):12-5. doi: 10.1177/0049475515592283. Epub 2015 Jul 8.
Amoebic liver abscess is a serious but curable hepatic illness predominantly seen in tropical countries. We describe our experience of clinical presentation, laboratory parameters, radiological findings and treatment strategies. This is a retrospective analysis of 114 patients who were admitted from January 2012 to September 2014 at our centre. The mean age of presentation was 41.7 ± 13.9 years, the majority of patients were male (86.8%) with chronic alcoholism (63.2%). Most of the patients had a solitary right lobe liver abscess. Abdominal pain, fever, tachycardia and hepatomegaly were the most common clinical findings while hypoalbuminaemia, anaemia, leucocytosis and electrolyte imbalance were the most common laboratory abnormalities. A significant number of patients could be managed with antibiotics only (45.6%), percutaneous radiological drainage techniques being an important adjunct in selected cases (percutaneous needle aspiration, 20.2%; percutaneous pigtail catheter drainage, 30.7%). Surgical intervention was required in only a few cases (3.5%). Mortality was 3.5%.
阿米巴肝脓肿是一种严重但可治愈的肝脏疾病，主要见于热带国家。我们描述了我们在临床表现、实验室参数、影像学检查结果及治疗策略方面的经验。这是一项对2012年1月至2014年9月在我们中心收治的114例患者的回顾性分析。患者的平均就诊年龄为41.7±13.9岁，大多数患者为男性（86.8%），并有慢性酒精中毒（63.2%）。大多数患者有单个右叶肝脓肿。腹痛、发热、心动过速和肝肿大是最常见的临床表现，而低白蛋白血症、贫血、白细胞增多和电解质失衡是最常见的实验室异常。相当一部分患者仅用抗生素即可治疗（45.6%），经皮放射引流技术在某些病例中是重要的辅助手段（经皮针吸，20.2%；经皮猪尾导管引流，30.7%）。仅少数病例需要手术干预（3.5%）。死亡率为3.5%。
