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皮肌炎表现为副肿瘤综合征,在对潜在的乳腺恶性肿瘤进行手术治疗后症状得以缓解。

Dermatomyositis presenting as a paraneoplastic syndrome with resolution of symptoms following surgical management of underlying breast malignancy.

作者信息

Luu Xuan, Leonard Samantha, Joseph Kathie-Ann

机构信息

Department of Surgery, Bellevue Medical Center, New York University School of Medicine, New York, NY, USA.

Department of Surgery, Bellevue Medical Center, New York University School of Medicine, New York, NY, USA

出版信息

J Surg Case Rep. 2015 Jul 7;2015(7):rjv075. doi: 10.1093/jscr/rjv075.

Abstract

Breast cancer is the most common cancer in women in the USA, with the lifetime incidence of 1 in 8 women. Dermatomyositis (DM) is an uncommon idiopathic inflammatory myopathy that can manifest as a paraneoplastic syndrome of an underlying malignancy. Here, we report a case of a patient who presented with breast cancer and DM symptoms. The patient's rash and muscle weakness progressed during the workup of her breast cancer, while she was already started on medical treatment of these symptoms with oral prednisone. Her cutaneous and musculoskeletal improved dramatically following the treatment of her breast cancer. Our case report describes the rapid progression and regression of her symptoms emphasizing the benefit of early diagnosis and treatment of DM as well as the underlying breast cancer.

摘要

乳腺癌是美国女性中最常见的癌症,八分之一的女性一生中会患乳腺癌。皮肌炎(DM)是一种罕见的特发性炎性肌病,可表现为潜在恶性肿瘤的副肿瘤综合征。在此,我们报告一例出现乳腺癌和皮肌炎症状的患者。该患者在乳腺癌检查期间皮疹和肌肉无力症状加重,而此时她已开始口服泼尼松对这些症状进行药物治疗。在乳腺癌治疗后,她的皮肤和肌肉骨骼症状显著改善。我们的病例报告描述了她症状的快速进展和消退,强调了早期诊断和治疗皮肌炎以及潜在乳腺癌的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f90/4495251/113f7790d571/rjv07501.jpg

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