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走钢丝:一例耐药性皮肌炎合并结核性淋巴结炎和梅毒瘤患者的隐匿性淋巴瘤

Walking a Tight Rope: Occult Lymphoma in a Case of Resistant Dermatomyositis Complicated by Tubercular Lymphadenitis and Gumma.

作者信息

Chhabra Namrata, Rahim Jemshi S, Ganguly Satyaki

机构信息

From the Department of Dermatology, AIIMS, Raipur, Chhattisgarh, India.

出版信息

Indian J Dermatol. 2024 Jul-Aug;69(4):365. doi: 10.4103/ijd.ijd_214_23. Epub 2024 Aug 19.

Abstract

Dermatomyositis (DM) is an autoimmune inflammatory disease, characterized by symmetrical proximal myopathy and cutaneous manifestations. DM is associated with upto a 6-fold increased risk of cancer. Complications secondary to underlying cancer are a leading cause of mortality in DM. Here, we discuss the two year clinical course of an elderly male with recalcitrant DM. This case was complicated by tubercular lymphadenitis followed by gumma. Subsequently, he was diagnosed with lymphoma and succumbed to death. This case emphasizes the need to do extensive malignancy screening at regular intervals in DM.

摘要

皮肌炎(DM)是一种自身免疫性炎症性疾病,其特征为对称性近端肌无力和皮肤表现。皮肌炎与高达6倍的癌症风险增加相关。潜在癌症继发的并发症是皮肌炎患者死亡的主要原因。在此,我们讨论一名患有顽固性皮肌炎的老年男性的两年临床病程。该病例并发结核性淋巴结炎,随后出现梅毒瘤。随后,他被诊断为淋巴瘤并最终死亡。该病例强调了对皮肌炎患者定期进行广泛恶性肿瘤筛查的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bff9/11407574/e89ada68b386/IJD-69-365d-g001.jpg

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