Allouch Ali, Zaatarikahale Teisir B, Moussa Mohamad K, Jounblat Youssef, Bitar Nizar
Oncology, Lebanese University, Faculty of Medical Sciences, Beirut, LBN.
Internal Medicine, Lebanese University, Faculty of Medical Sciences, Beirut, LBN.
Cureus. 2020 Sep 23;12(9):e10624. doi: 10.7759/cureus.10624.
Dermatomyositis (DM) is a rare idiopathic inflammatory myopathy, which is associated with malignancy in 15%-30% of cases. Breast cancer, the most frequent malignancy diagnosed in women, can feature uncommon presentations, such as paraneoplastic syndrome including DM. The aim of this case is to promote awareness regarding any adult patient who presents with DM for early detection and treatment of a possible underlying malignancy. Our patient was diagnosed and treated for DM without any improvement, until she presented to our department, and after a comprehensive history and physical exam, an underlying breast cancer was detected. It was metastatic unfortunately, but she improved after treatment with regression of symptoms related to DM.
皮肌炎(DM)是一种罕见的特发性炎性肌病,15% - 30%的病例与恶性肿瘤相关。乳腺癌是女性中最常诊断出的恶性肿瘤,可能有不常见的表现,如包括皮肌炎在内的副肿瘤综合征。本病例的目的是提高对任何出现皮肌炎的成年患者的认识,以便早期发现和治疗可能潜在的恶性肿瘤。我们的患者被诊断为皮肌炎并接受了治疗,但没有任何改善,直到她来到我们科室,经过全面的病史询问和体格检查后,发现了潜在的乳腺癌。不幸的是,已经发生转移,但她在接受治疗后症状有所改善,与皮肌炎相关的症状出现了消退。