Varshney Poorti, Saini Renuka, Taneja Ajay
Department of Chemistry, Dr. B. R. Ambedkar University, Khandari Campus, Agra, 282002, India.
Environ Geochem Health. 2016 Apr;38(2):593-605. doi: 10.1007/s10653-015-9745-5. Epub 2015 Jul 10.
Exposure to airborne particulate matter results in the deposition of millions of particle in the lung; consequently, there is need for monitoring them particularly in indoor environments. Case study was conducted in three different microenvironments, i.e., urban, rural and roadside to examine the elemental bioavailability in fine particulate matter and its potential health risk. The samples were collected on polytetrafluoroethylene filter paper with the help of fine particulate sampler during August-September, 2012. The average mass concentration of PM2.5 was 71.23 µg m(-3) (rural), 45.33 µg m(-3) (urban) and 36.71 µg m(-3) (roadside). Elements in PM2.5 were analyzed by inductively coupled plasma atomic emission spectroscopy. Percentage bioavailability was determined to know the amount of soluble fraction that is actually taken across the cell membrane through inhalation pathway. Cadmium and lead were found to have cancer risk in a risk evaluation using an Integrated Risk Information system.
暴露于空气中的颗粒物会导致数百万个颗粒沉积在肺部；因此，尤其在室内环境中需要对其进行监测。在城市、农村和路边这三种不同的微环境中进行了案例研究，以检查细颗粒物中的元素生物可利用性及其潜在健康风险。2012年8月至9月期间，借助细颗粒物采样器在聚四氟乙烯滤纸上采集样本。PM2.5的平均质量浓度分别为71.23微克/立方米（农村）、45.33微克/立方米（城市）和36.71微克/立方米（路边）。通过电感耦合等离子体原子发射光谱法分析PM2.5中的元素。通过测定生物可利用百分比来了解通过吸入途径实际穿过细胞膜的可溶部分的量。在使用综合风险信息系统进行的风险评估中，发现镉和铅存在致癌风险。
