Kallio Peter J, Nolan Jenea, Olsen Amy C, Breakwell Susan, Topp Richard, Pagel Paul S
Anesthesia Service, Clement J. Zablocki Veterans Affairs Medical Center, Milwaukee, Wisconsin, USA ; Department of Nursing, Marquette University, Wisconsin, USA.
The School of Nurse Anesthesia, Rosalind Franklin University is located in Chicago, Illinois, USA.
Anesth Pain Med. 2015 Jun 22;5(3):e24376. doi: 10.5812/aapm.5(3)2015.24376. eCollection 2015 Jun.
Diabetes mellitus (DM) is risk factor for complications after orthopedic surgery.
We tested the hypothesis that anesthesia preoperative clinic (APC) referral for elevated glycosylated hemoglobin (HbA1c) reduces complication rate after total joint arthroplasty (TJA).
Patients (n = 203) with and without DM were chosen from 1,237 patients undergoing TJA during 2006 - 12. Patients evaluated in the APC had surgery in 2006 - 8 regardless of HbA1c (uncontrolled). Those evaluated between in subsequent two-year intervals were referred to primary care for HbA1c ≥ 10% and ≥ 8%, respectively, to improve DM control before surgery. Complications and mortality were quantified postoperatively and at three, six, and twelve months. Length of stay (LOS) and patients requiring a prolonged LOS (> 5 days) were recorded.
Patients (197 men, 6 women) underwent 71, 131, and 1 total hip, knee, and shoulder replacements, respectively. Patients undergoing TJA with uncontrolled HbA1c and those with HbA1c < 10%, but not those with HbA1c < 8%, had a higher incidence of coronary disease and hypercholesterolemia than patients without DM. An increase in complication rate was observed in DM patients with uncontrolled HbA1c versus patients without DM (P < 0.001); the complication rate progressively decreased with tighter HbA1c control. More DM patients with preoperative HbA1c that was uncontrolled or ≥ 10% required prolonged LOS versus those without DM (P < 0.001 and P = 0.0404, respectively).
APC referral for elevated HbA1c reduces complication rate and the incidence of prolonged hospitalization during the first year after surgery in diabetics undergoing TJA.
糖尿病(DM)是骨科手术后发生并发症的危险因素。
我们检验了以下假设,即因糖化血红蛋白(HbA1c)升高而转诊至麻醉术前门诊(APC)可降低全关节置换术(TJA)后的并发症发生率。
从2006年至2012年期间接受TJA的1237例患者中选取有或无DM的患者(n = 203例)。在APC接受评估的患者于2006年至2008年进行手术,无论其HbA1c水平如何(未得到控制)。在随后两年期间接受评估的患者,若HbA1c≥10%和≥8%,则分别被转诊至初级保健机构,以在手术前改善糖尿病控制。对术后以及术后3个月、6个月和12个月的并发症和死亡率进行量化。记录住院时间(LOS)以及需要延长住院时间(>5天)的患者情况。
患者(197例男性,6例女性)分别接受了71例全髋关节置换、131例全膝关节置换和1例全肩关节置换。与无DM的患者相比,HbA1c未得到控制的TJA患者以及HbA1c<10%但非HbA1c<8%的患者,冠心病和高胆固醇血症的发生率更高。与无DM的患者相比,HbA1c未得到控制的糖尿病患者并发症发生率增加(P<0.001);随着HbA1c控制得更严格,并发症发生率逐渐降低。与无DM的患者相比,术前HbA1c未得到控制或≥10%的糖尿病患者需要延长住院时间的更多(分别为P<0.001和P = 0.0404)。
因HbA1c升高而转诊至APC可降低接受TJA的糖尿病患者术后第一年的并发症发生率以及延长住院时间的发生率。