相似文献
1
Catalytically Important Residues of E6AP Ubiquitin Ligase Identified Using Acid-Cleavable Photo-Cross-Linkers.
Biochemistry. 2015 Jul 28;54(29):4411-4. doi: 10.1021/acs.biochem.5b00625. Epub 2015 Jul 20.
2
modeling of the cryptic E2∼ubiquitin-binding site of E6-associated protein (E6AP)/UBE3A reveals the mechanism of polyubiquitin chain assembly.
J Biol Chem. 2017 Nov 3;292(44):18006-18023. doi: 10.1074/jbc.M117.813477. Epub 2017 Sep 18.
3
The active form of E6-associated protein (E6AP)/UBE3A ubiquitin ligase is an oligomer.
J Biol Chem. 2014 Jan 10;289(2):1033-48. doi: 10.1074/jbc.M113.517805. Epub 2013 Nov 22.
4
An Angelman syndrome substitution in the HECT E3 ubiquitin ligase C-terminal Lobe of E6AP affects protein stability and activity.
PLoS One. 2020 Jul 8;15(7):e0235925. doi: 10.1371/journal.pone.0235925. eCollection 2020.
5
Analysis of ubiquitin recognition by the HECT ligase E6AP provides insight into its linkage specificity.
J Biol Chem. 2019 Apr 12;294(15):6113-6129. doi: 10.1074/jbc.RA118.007014. Epub 2019 Feb 8.
6
Identification of Small-Molecule Activators of the Ubiquitin Ligase E6AP/UBE3A and Angelman Syndrome-Derived E6AP/UBE3A Variants.
Cell Chem Biol. 2020 Dec 17;27(12):1510-1520.e6. doi: 10.1016/j.chembiol.2020.08.017. Epub 2020 Sep 22.
7
Ubiquitin chain specificities of E6AP E3 ligase and its HECT domain.
Biochem Biophys Res Commun. 2018 Feb 5;496(2):686-692. doi: 10.1016/j.bbrc.2017.12.076. Epub 2017 Dec 27.
8
c-Abl phosphorylates E6AP and regulates its E3 ubiquitin ligase activity.
Biochemistry. 2013 May 7;52(18):3119-29. doi: 10.1021/bi301710c. Epub 2013 Apr 26.
9
Role of ubiquitin and the HPV E6 oncoprotein in E6AP-mediated ubiquitination.
Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):9872-7. doi: 10.1073/pnas.1505923112. Epub 2015 Jul 27.
10
Cobalamins Function as Allosteric Activators of an Angelman Syndrome-Associated UBE3A/E6AP Variant.
Chembiochem. 2024 May 17;25(10):e202400184. doi: 10.1002/cbic.202400184. Epub 2024 May 2.
引用本文的文献
1
Chemical Tools for Probing the Ub/Ubl Conjugation Cascades.
Chembiochem. 2025 Jan 2;26(1):e202400659. doi: 10.1002/cbic.202400659. Epub 2024 Nov 6.
2
LiF-MS+, a revised technique for mapping peptide-protein interactions.
bioRxiv. 2024 May 29:2024.05.28.596279. doi: 10.1101/2024.05.28.596279.
3
Decoding the messaging of the ubiquitin system using chemical and protein probes.
Cell Chem Biol. 2021 Jul 15;28(7):889-902. doi: 10.1016/j.chembiol.2021.03.009. Epub 2021 Apr 7.
4
Photocrosslinking Activity-Based Probes for Ubiquitin RING E3 Ligases.
Cell Chem Biol. 2020 Jan 16;27(1):74-82.e6. doi: 10.1016/j.chembiol.2019.11.013. Epub 2019 Dec 16.
5
Mapping low-affinity/high-specificity peptide-protein interactions using ligand-footprinting mass spectrometry.
Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21001-21011. doi: 10.1073/pnas.1819533116. Epub 2019 Oct 2.
本文引用的文献
1
Strategy for "detoxification" of a cancer-derived histone mutant based on mapping its interaction with the methyltransferase PRC2.
J Am Chem Soc. 2014 Oct 1;136(39):13498-501. doi: 10.1021/ja5060934. Epub 2014 Sep 19.
2
The active form of E6-associated protein (E6AP)/UBE3A ubiquitin ligase is an oligomer.
J Biol Chem. 2014 Jan 10;289(2):1033-48. doi: 10.1074/jbc.M113.517805. Epub 2013 Nov 22.
3
Development of activity-based probes for ubiquitin and ubiquitin-like protein signaling pathways.
J Am Chem Soc. 2013 Nov 13;135(45):16948-62. doi: 10.1021/ja4099643. Epub 2013 Nov 1.
4
E6AP/UBE3A ubiquitin ligase harbors two E2~ubiquitin binding sites.
J Biol Chem. 2013 Apr 12;288(15):10349-60. doi: 10.1074/jbc.M113.458059. Epub 2013 Feb 25.
5
Identification of cross-linked peptides from complex samples.
Nat Methods. 2012 Sep;9(9):904-6. doi: 10.1038/nmeth.2099. Epub 2012 Jul 8.
6
The ubiquitin system, an immense realm.
Annu Rev Biochem. 2012;81:167-76. doi: 10.1146/annurev-biochem-051910-094049.
7
Kinetics of the transfer of ubiquitin from UbcH7 to E6AP.
Biochemistry. 2010 Feb 23;49(7):1361-3. doi: 10.1021/bi9014693.
8
The ubiquitin-interacting motif protein, S5a, is ubiquitinated by all types of ubiquitin ligases by a mechanism different from typical substrate recognition.
J Biol Chem. 2009 May 8;284(19):12622-32. doi: 10.1074/jbc.M900556200. Epub 2009 Feb 24.
9
Gel-eluted liquid fraction entrapment electrophoresis: an electrophoretic method for broad molecular weight range proteome separation.
Anal Chem. 2008 Mar 1;80(5):1568-73. doi: 10.1021/ac702197w. Epub 2008 Jan 30.
10
Photo-leucine incorporation reveals the target of a cyclodepsipeptide inhibitor of cotranslational translocation.
J Am Chem Soc. 2007 Nov 28;129(47):14560-1. doi: 10.1021/ja076250y. Epub 2007 Nov 6.
Zotero 插件