Bae Jungbum, Kang Hyoun Woo, Lee Hae Won, Lee Kwang Soo, Cho Min Chul
Department of Urology, Dongguk University College of Medicine, 814, Siksa-Dong, Ilsandong-Gu, Goyang-Si, 410-773, Korea.
Department of Internal Medicine, Dongguk University College of Medicine, Goyang-Si, Korea.
World J Urol. 2016 Mar;34(3):413-8. doi: 10.1007/s00345-015-1635-z. Epub 2015 Jul 11.
To investigate serial changes in the incidences of de novo urge urinary incontinence (UUI) after photoselective vaporization of the prostate (PVP) for BPH using a validated questionnaire, OABSS, and to determine predictors of postoperative de novo UUI (dnUUI).
A total of 84 men, for whom 12-month follow-up data were available and who did not complain of UUI based on the OABSS [score of OABSS question 4 (OABSS4) ≤1], were included in this study. Outcomes were evaluated at 1 week, and 1, 3, 6, and 12 months postoperatively using IPSS, OABSS, and uroflowmetry. The presence of de novo UUI was defined as OABSS4 ≥2 at the follow-up visit.
Maximum flow rate (Qmax), post-void residual urine volume, voiding symptom score, total IPSS, and QOL index improved from 1 week. Storage symptom score and total OABSS improved from 3 months. Incidences of postoperative dnUUI at 1 week, and 1, 3, and 6 months were 42.9, 27.4, 14.3, and 0.0 %, respectively. The decrease in QOL index in patients with dnUUI at each follow-up visit was lesser than in those without dnUUI. On multivariate regression analysis, older age, shorter time to Qmax on baseline uroflowmetry, higher storage symptom score, higher total OABSS, smaller bladder volume at first desire to void, and smaller maximum cystometric capacity (MCC) on baseline urodynamics were independent predictors of occurrence of dnUUI.
Our data indicate that transient dnUUI occurs in a significant proportion of patients after PVP and it tends to decrease over time. Older-aged patients, patients with shorter time to Qmax, higher baseline storage symptom score, higher baseline total OABSS, smaller bladder volume at first desire to void, and smaller MCC may be prone to develop dnUUI postoperatively.
使用经过验证的问卷OABSS,调查良性前列腺增生(BPH)患者接受前列腺光选择性汽化术(PVP)后新发急迫性尿失禁(UUI)发生率的系列变化,并确定术后新发UUI(dnUUI)的预测因素。
本研究纳入了84名男性,他们有12个月的随访数据,且根据OABSS[OABSS问题4(OABSS4)评分≤1]无UUI主诉。在术后1周、1、3、6和12个月使用国际前列腺症状评分(IPSS)、OABSS和尿流率测定评估结果。新发UUI的存在定义为随访时OABSS4≥2。
最大尿流率(Qmax)、排尿后残余尿量、排尿症状评分、总IPSS和生活质量指数从术后1周开始改善。储尿症状评分和总OABSS从术后3个月开始改善。术后1周、1、3和6个月时dnUUI的发生率分别为42.9%、27.4%、14.3%和0.0%。每次随访时dnUUI患者的生活质量指数下降幅度小于无dnUUI的患者。多因素回归分析显示,年龄较大、基线尿流率测定时达到Qmax的时间较短、储尿症状评分较高、总OABSS较高、首次有排尿欲望时膀胱容量较小以及基线尿动力学检查时最大膀胱测压容量(MCC)较小是dnUUI发生的独立预测因素。
我们的数据表明,PVP术后相当比例的患者会出现短暂的dnUUI,且其发生率会随时间下降。年龄较大的患者、达到Qmax时间较短的患者、基线储尿症状评分较高的患者、基线总OABSS较高的患者、首次有排尿欲望时膀胱容量较小的患者以及MCC较小的患者术后可能更容易发生dnUUI。