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开发和验证一种列线图,用于预测前列腺内镜剜除术后早期压力性尿失禁。

Development and validation of a nomogram for predicting early stress urinary incontinence following endoscopic enucleation of the prostate.

机构信息

Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.

Department of Urology, Xinhua Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, People's Republic of China.

出版信息

World J Urol. 2021 Sep;39(9):3447-3453. doi: 10.1007/s00345-021-03592-x. Epub 2021 Jan 21.

Abstract

PURPOSE

To develop and validate a predictive nomogram for early stress urinary incontinence (SUI) after endoscopic enucleation of the prostate (EEP) in patients with benign prostatic hyperplasia (BPH).

METHODS

The records of 458 patients who underwent plasmakinetic- or diode-based EEP at our center from March 2016 to December 2019 were reviewed. Among these, 326 and 132 cases were randomly assigned to the training and validation set, respectively. A predictive nomogram was constructed based on multivariate logistic regression analysis. Receiver operating characteristic (ROC) analysis and calibration curves were employed to evaluate its performance.

RESULTS

65 years ≤ age < 70 years, 75 years ≤ age, 25 kg/m ≤ BMI < 30 kg/m, 30 kg/m ≤ BMI, 5 years ≤ LUTS duration, and 75 ml ≤ prostate volume were finally selected as independent predictors of early SUI into the multivariate logistics regression model. It was visualized as a concise nomogram with satisfactory discrimination and accuracy in both training and validation sets.

CONCLUSIONS

A concise nomogram was developed and validated as a useful clinical tool for predicting early SUI post-EEP.

摘要

目的

为了开发并验证一种用于预测良性前列腺增生(BPH)患者经内镜前列腺剜除术后早期压力性尿失禁(SUI)的预测列线图。

方法

回顾了 2016 年 3 月至 2019 年 12 月在我们中心接受等离子体剜除术或二极管剜除术的 458 例患者的记录。其中,326 例和 132 例患者被随机分配到训练集和验证集中。基于多变量逻辑回归分析构建预测列线图。采用受试者工作特征(ROC)分析和校准曲线评估其性能。

结果

年龄≥65 岁且<70 岁、年龄≥75 岁、体重指数(BMI)25kg/m²≤BMI<30kg/m²、BMI≥30kg/m²、LUTS 持续时间≥5 年和前列腺体积≥75ml 被最终选为早期 SUI 的独立预测因子进入多变量逻辑回归模型。该模型以简洁的列线图形式呈现,在训练集和验证集中均具有良好的区分度和准确性。

结论

开发并验证了一种用于预测经内镜前列腺剜除术后早期 SUI 的简洁列线图,是一种有用的临床工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d56b/8510930/e0b1efaf5884/345_2021_3592_Fig1_HTML.jpg

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