Linde Johanna, Rück Christian, Bjureberg Johan, Ivanov Volen Z, Djurfeldt Diana Radu, Ramnerö Jonas
Karolinska Institutet; Stockholm University.
Karolinska Institutet.
Behav Ther. 2015 Jul;46(4):423-31. doi: 10.1016/j.beth.2015.05.002. Epub 2015 May 21.
Body dysmorphic disorder (BDD) is an often severe, chronic, and disabling disorder, and although some controlled trials of cognitive behavior therapy (CBT) have shown efficacy, the body of evidence is still limited. The condition is generally considered difficult to treat, and further research to determine the effectiveness of psychological treatments for BDD is needed. The present study is the first to evaluate an acceptance-based therapy for BDD. In total, 21 patients received a 12-week group treatment consisting of weekly sessions of psychoeducation, acceptance and defusion practice, and exposure exercises to foster acceptance of internal discomfort and to strengthen the patients' committed purposeful actions. The primary outcome was BDD symptomatology (measured on the BDD-YBOCS) assessed by a psychiatrist before and after treatment and at 6months follow-up. The secondary outcomes were self-rated BDD symptoms, psychological flexibility, depressive symptoms, quality of life, and disability. Reductions in BDD symptomatology from pre- to posttreatment were significant and showed a large effect size, d=1.93 (95% CI 0.82-3.04). At posttreatment, 68% of the participants showed clinically significant improvement in the primary outcome variable. Treatment gains were maintained at 6months follow-up. The treatment also resulted in significant improvements in all secondary outcomes. The dropout rate was low; 90.5% of the participants completed treatment. This study suggests that acceptance-based exposure therapy may be an efficacious and acceptable treatment for BDD that warrants further investigation in larger controlled trials.
躯体变形障碍(BDD)是一种通常较为严重、慢性且致残的疾病,尽管一些认知行为疗法(CBT)的对照试验已显示出疗效,但证据仍有限。这种疾病通常被认为难以治疗,因此需要进一步研究以确定针对BDD的心理治疗效果。本研究首次评估了一种基于接纳的BDD治疗方法。共有21名患者接受了为期12周的团体治疗,包括每周一次的心理教育、接纳与解离练习,以及暴露练习,以促进对内在不适的接纳并加强患者坚定的有目的行动。主要结局是由精神科医生在治疗前、治疗后以及6个月随访时通过BDD-YBOCS评估的BDD症状学。次要结局包括自评BDD症状、心理灵活性、抑郁症状、生活质量和残疾情况。从治疗前到治疗后,BDD症状学的降低具有显著性,且效应量较大,d = 1.93(95%CI 0.82 - 3.04)。在治疗后,68%的参与者在主要结局变量上显示出临床显著改善。治疗效果在6个月随访时得以维持。该治疗还导致所有次要结局均有显著改善。脱落率较低;90.5%的参与者完成了治疗。本研究表明,基于接纳的暴露疗法可能是一种对BDD有效且可接受的治疗方法,值得在更大规模的对照试验中进一步研究。