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经导管主动脉瓣置换术:主动脉根部尺寸测量的成像技术

Transcatheter Aortic Valve Replacement: Imaging Techniques for Aortic Root Sizing.

作者信息

Wichmann Julian L, Varga-Szemes Akos, Suranyi Pal, Bayer Richard R, Litwin Sheldon E, De Cecco Carlo N, Mangold Stefanie, Muscogiuri Giuseppe, Fuller Stephen R, Vogl Thomas J, Steinberg Daniel H, Schoepf U Joseph

机构信息

*Department of Radiology and Radiological Science, Division of Cardiovascular Imaging ‡Department of Medicine, Division of Cardiology, Medical University of South Carolina, Charleston, SC †Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt ∥Department of Diagnostic and Interventional Radiology, University Hospital of Tübingen, Tübingen, Germany §Department of Radiological Sciences, Oncology and Pathology, University of Rome "Sapienza" - Polo Pontino, Latina ¶Department of Medical-Surgical Sciences and Translational Medicine, University of Rome "Sapienza," Rome, Italy.

出版信息

J Thorac Imaging. 2015 Nov;30(6):349-58. doi: 10.1097/RTI.0000000000000167.

Abstract

Transcatheter aortic valve replacement (TAVR) is an increasingly used alternative to surgical aortic valve replacement in patients with severe aortic stenosis and prohibitive perioperative risk. Several studies have shown an improved clinical outcome and lower rate of complications with TAVR in this patient population. Furthermore, TAVR has shown promising results in patients at elevated risk from surgical aortic valve replacement. Because of the endovascular nature of this technique, comprehensive preprocedural assessment of the aortic root and vascular access path is crucial. Although echocardiography is still commonly performed to assess the aortic root, cross-sectional imaging modalities are increasingly used given their superior results in the diagnostic accuracy of TAVR measurements. In particular, computed tomography (CT) is gaining an increasing role in pre-TAVR imaging because of fast 3-dimensional assessment of aortic root anatomy and improvements in clinical outcome after TAVR when CT is used for pre-TAVR planning. However, different algorithms exist for matching valve size to the aortic root and left ventricular outflow tract, and these measurements may substantially impact valve prosthesis selection and postinterventional complication rates. Cardiac magnetic resonance may play a role especially in post-TAVR assessment, as it provides both anatomic information and blood flow dynamics. This article reviews multimodality imaging approaches to pre-TAVR aortic root size assessment, provides an overview of the impact on post-TAVR complications and clinical outcome, and describes recent techniques to reduce contrast material volume in TAVR assessment with CT.

摘要

经导管主动脉瓣置换术(TAVR)在严重主动脉瓣狭窄且围手术期风险极高的患者中,正日益成为外科主动脉瓣置换术的替代选择。多项研究表明,在这类患者群体中,TAVR可改善临床结局并降低并发症发生率。此外,TAVR在外科主动脉瓣置换术风险较高的患者中也显示出了良好的效果。由于该技术具有血管内介入的特性,对主动脉根部和血管入路进行全面的术前评估至关重要。尽管超声心动图仍常用于评估主动脉根部,但鉴于其在TAVR测量诊断准确性方面的优越表现,横断面成像方式的应用越来越广泛。特别是计算机断层扫描(CT),由于其能够快速对主动脉根部解剖结构进行三维评估,且在用于TAVR术前规划时可改善TAVR术后的临床结局,因此在TAVR术前成像中发挥着越来越重要的作用。然而,在将瓣膜尺寸与主动脉根部和左心室流出道进行匹配时存在不同的算法,这些测量可能会对瓣膜假体的选择和介入后并发症发生率产生重大影响。心脏磁共振成像可能尤其在TAVR术后评估中发挥作用,因为它既能提供解剖信息,又能提供血流动力学信息。本文回顾了TAVR术前主动脉根部尺寸评估的多模态成像方法,概述了其对TAVR术后并发症和临床结局的影响,并描述了近期在CT进行TAVR评估时减少造影剂用量的技术。

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