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枸橼酸镓67闪烁扫描术中的肺部摄取——“负心”征

Pulmonary uptake in 67-gallium citrate scintigraphy-the 'negative heart' sign.

作者信息

Cooke S G, Davies E R, Goddard P R

机构信息

Department of Radiodiagnosis, Bristol Royal Infirmary, UK.

出版信息

Postgrad Med J. 1989 Dec;65(770):885-91. doi: 10.1136/pgmj.65.770.885.

DOI:10.1136/pgmj.65.770.885
PMID:2616428
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2429576/
Abstract

Diffuse pulmonary uptake in 67-gallium citrate (67-Ga) scintigraphy occurs in a large number of neoplastic and inflammatory conditions. Discrimination between normal and abnormal 67-Ga uptake over the chest can be difficult and a simple visual method for identifying abnormal studies is described. A series of 39 gallium scintigrams was retrospectively reviewed by the authors and reported without knowledge of the patients' clinical condition. Subsequent clinical follow up was obtained to establish the accuracy of the scintigram interpretation. Comparison of pulmonary uptake with that over the cardiac area is recommended as a simple and reliable method of confirming that the level of pulmonary activity is abnormal. In highly abnormal cases the cardiac area is seen as a 'negative heart' image due to the considerably increased activity in the lungs. This sign is best seen with abnormal diffuse uptake but is also seen with abnormal focal uptake. Care must be taken, as the sign may be masked, if uptake over the cardiac area itself is increased.

摘要

枸橼酸镓(67-Ga)闪烁扫描中肺部弥漫性摄取见于大量肿瘤性和炎性疾病。区分胸部正常和异常的67-Ga摄取可能存在困难,本文描述了一种识别异常检查的简单视觉方法。作者回顾性分析了39例镓闪烁扫描图像,在不了解患者临床情况的前提下进行报告。随后进行临床随访以确定闪烁扫描图像解读的准确性。建议将肺部摄取与心脏区域的摄取进行比较,作为确认肺部活性水平异常的简单可靠方法。在高度异常的病例中,由于肺部活性显著增加,心脏区域可呈现“负心”影像。此征象在异常弥漫性摄取时最易观察到,但在异常局灶性摄取时也可出现。如果心脏区域本身的摄取增加,该征象可能会被掩盖,必须加以注意。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f858/2429576/567f3ff55059/postmedj00180-0022-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f858/2429576/301730790ff1/postmedj00180-0021-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f858/2429576/567f3ff55059/postmedj00180-0022-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f858/2429576/301730790ff1/postmedj00180-0021-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f858/2429576/567f3ff55059/postmedj00180-0022-a.jpg

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本文引用的文献

1
Gallium-67 scanning to stage the alveolitis of sarcoidosis: correlation with clinical studies, pulmonary function studies, and bronchoalveolar lavage.用镓-67扫描对结节病肺泡炎进行分期:与临床研究、肺功能研究及支气管肺泡灌洗的相关性
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Gallium-67 citrate imaging studies of the lung.肺的枸橼酸镓-67显像研究
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Quantitation of pulmonary gallium-67 uptake: comparison of computer-derived indices.肺镓-67摄取量的定量分析:计算机衍生指标的比较
Nucl Med Commun. 1985 Jul;6(7):425-33. doi: 10.1097/00006231-198507000-00008.
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Standardized quantitative 67Ga scintigraphy in pulmonary sarcoidosis.
Sarcoidosis. 1988 Sep;5(2):111-8.
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Gallium-67 scintigraphy of pulmonary diseases as a complement to radiography.镓-67肺疾病闪烁扫描术作为X线摄影的补充手段
Radiology. 1976 Feb;118(2):371-5. doi: 10.1148/118.2.371.