Ditto Antonino, Martinelli Fabio, Bogani Giorgio, Gasparri Maria L, Donato Violante Di, Paolini Biagio, Carcangiu Maria L, Lorusso Domenica, Raspagliesi Francesco
Department of Gynecologic Oncology, IRCCS National Cancer Institute, Milan - Italy.
Department of Pathology, IRCCS National Cancer Institute, Milan - Italy.
Tumori. 2016 Nov 11;102(Suppl. 2):9D10FC9F-46CA-43EB-92F5-FFC7BC6A1DE5. doi: 10.5301/tj.5000386.
Malignant mesonephric adenocarcinoma of the uterine cervix is a rare occurrence with few cases described in the literature. Although surgery seems to be effective in the treatment of early-stage tumor, no cases describing outcomes of locally advanced stage are available.
We report the first case of a patient with International Federation of Obstetrics and Gynecologists stage IIB mesonephric adenocarcinoma undergoing neoadjuvant chemotherapy and radical surgery.
Despite the inherent limitation of a single description of a case, our experience supports the utilization of neoadjuvant chemotherapy in patients with malignant mesonephric adenocarcinoma of the uterine cervix. Further prospective multi-institutional studies are needed.