Exley A, O'Malley B P
Leicester Royal Infirmary.
Q J Med. 1989 Sep;72(269):867-70.
Depression may occasionally be a presenting feature of primary hypothyroidism but the influence of psychological illness upon L-thyroxine compliance in hypothyroidism has not been specifically addressed. We report six patients with primary hypothyroidism in whom repeated thyroid function tests implied that they were not taking their L-thyroxine as prescribed. The eventual recognition of underlying depression and its treatment led to appropriate treatment with thyroxine as evidenced by clinical euthyroidism and normal thyroid function tests.
抑郁症偶尔可能是原发性甲状腺功能减退症的一个表现特征,但心理疾病对甲状腺功能减退症患者左甲状腺素依从性的影响尚未得到专门研究。我们报告了6例原发性甲状腺功能减退症患者,反复的甲状腺功能检查表明他们未按规定服用左甲状腺素。最终识别出潜在的抑郁症并进行治疗,随后甲状腺素得到了恰当治疗,临床甲状腺功能正常及甲状腺功能检查结果正常证明了这一点。