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胎儿口咽及颈部肿瘤:确定宫外产时治疗程序的必要性。

Fetal Oropharyngeal and Neck Tumors: Determination of the Need for Ex-Utero Intrapartum Treatment Procedure.

作者信息

Özgünen Fatma Tuncay, Güleç Ümran Küçükgöz, Evrüke İsmail Cüneyt, Demir Süleyman Cansun, Büyükkurt Selim, Yapıcıoğlu Hacer, İskit Serdar

机构信息

Department of Obstetrics and Gynecology, Çukurova University Faculty of Medicine, Adana, Turkey.

Department of Pediatrics Neonatalogy Unit, Çukurova University Faculty of Medicine, Adana, Turkey.

出版信息

Balkan Med J. 2015 Apr;32(2):221-5. doi: 10.5152/balkanmedj.2015.150096. Epub 2015 Apr 1.

Abstract

BACKGROUND

The aim of this study was to assess the ex-utero intrapartum therapy (EXIT) applied to 3 of the 7 cases with oropharyngeal or neck masses and review the indicators of the need for an EXIT procedure.

CASE REPORT

Prenatal presentation, size and localization of the masses, existence of fetal hydrops and associated findings such as polyhydramnios, intraoperative managements, complications, and maternal and neonatal outcomes were evaluated through a retrospective analysis. Four cases had neck masses and three cases had oropharyngeal masses. Prenatal sonography was used as the main diagnostic tool for all patients. The median gestational age was 34.5 weeks at the time of diagnosis and 36 weeks at delivery. Polyhydramnios was observed in three of the seven cases and they were delivered prematurely. Interventions such as endotracheal intubation or tracheostomy were performed to provide patency of the airway during delivery by the EXIT procedure in three cases. Hemangioma was found in two cases, teratoma in two cases, lymphangioma in two cases and hamartoma in one case following pathological examination of the masses.

CONCLUSION

The localization of mass, its characteristics, invasion (if it exists), and relation to the airway are the main factors used to determine the need for EXIT. The presence of polyhydramnios may be an important indicator to predict both the need for EXIT and fetal outcomes.

摘要

背景

本研究的目的是评估在7例口咽或颈部肿物病例中的3例应用产时宫外治疗(EXIT),并回顾EXIT手术必要性的指标。

病例报告

通过回顾性分析评估产前肿物的表现、大小和位置、胎儿水肿的存在以及羊水过多等相关发现、术中管理、并发症以及母婴结局。4例有颈部肿物,3例有口咽肿物。所有患者均以产前超声作为主要诊断工具。诊断时的中位孕周为34.5周,分娩时为36周。7例中有3例观察到羊水过多,均为早产。3例通过EXIT手术在分娩期间进行了气管插管或气管切开等干预以保持气道通畅。肿物病理检查后发现2例为血管瘤,2例为畸胎瘤,2例为淋巴管瘤,1例为错构瘤。

结论

肿物的位置、特征、侵犯情况(如果存在)以及与气道的关系是决定是否需要EXIT的主要因素。羊水过多的存在可能是预测EXIT必要性和胎儿结局的重要指标。

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