Butwick Alexander, Aleshi Pedram, Yamout Imad
Department of Anesthesia (MC:5640), Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA, 94305, USA.
Can J Anaesth. 2009 Jun;56(6):437-42. doi: 10.1007/s12630-009-9092-z. Epub 2009 Apr 25.
To report a case of massive obstetric hemorrhage occurring during Cesarean delivery for an ex utero intrapartum treatment (EXIT) procedure. Methods to optimize the anesthetic, obstetric, and perinatal management are discussed.
A healthy parturient underwent an urgent EXIT procedure at 32 weeks gestation for a giant fetal neck mass. During the intraoperative period, severe intraoperative hemorrhage occurred from the site of the uterine incision. No evidence of placental bleeding, premature placental separation, or inadequate uterine relaxation was observed during the perioperative period. Placement of a uterine stapling device was unsuccessful in achieving adequate surgical hemostasis. Initial attempts with laryngoscopy and rigid bronchoscopy to secure the fetal airway on placental support were unsuccessful, and early termination of placental support was deemed necessary due to the severity of maternal blood loss. After full delivery of the neonate and termination of placental support, neonatal ventilation with bag-mask ventilation was achieved and successful endotracheal intubation occurred during repeat bronchoscopy.
The risk of obstetric hemorrhage due to uterine relaxation and inadequate surgical hemostasis in patients undergoing EXIT procedures is poorly reported. To reduce adverse maternal and neonatal outcomes, the premature termination of placental support during EXIT procedures may be required in the setting of severe obstetric hemorrhage.
报告1例在剖宫产术中进行产时宫外治疗(EXIT)手术时发生大量产科出血的病例。讨论优化麻醉、产科和围产期管理的方法。
一名健康的产妇在妊娠32周时因巨大胎儿颈部肿块接受了紧急EXIT手术。术中,子宫切口处发生严重术中出血。围手术期未观察到胎盘出血、胎盘早剥或子宫松弛不足的迹象。放置子宫吻合器未能实现充分的手术止血。最初尝试通过喉镜和硬质支气管镜在胎盘支持下确保胎儿气道,但未成功,由于产妇失血严重,认为有必要提前终止胎盘支持。新生儿完全娩出并终止胎盘支持后,通过面罩通气实现了新生儿通气,并在重复支气管镜检查期间成功进行了气管插管。
关于EXIT手术患者因子宫松弛和手术止血不充分导致产科出血的风险报道较少。为降低母婴不良结局,在严重产科出血的情况下,EXIT手术期间可能需要提前终止胎盘支持。