Zhang Peipei, Wu Xining, Ouyang Yunshu, Yang Tianrui, Zhang Yixiu, You Hui, Lv Yan, Jiang Yulin, Dai Qing, Meng Hua
Department of Ultrasound, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Front Pediatr. 2025 Aug 14;13:1516356. doi: 10.3389/fped.2025.1516356. eCollection 2025.
This study retrospectively analyzed the prenatal ultrasound features and outcomes of fetal neck masses to improve the understanding of fetal neck masses and provide evidence for prenatal consultation, prognosis assessment, delivery mode selection, and clinical intervention.
From January 2018 to November 2023, 18 patients who underwent routine prenatal ultrasonography in the ultrasound department of Peking Union Medical College Hospital or who were referred to our hospital for the diagnosis of a fetal neck mass were retrospectively identified. Their prenatal ultrasound characteristics and pregnancy outcomes were examined and follow-up was conducted.
There were 18 cases of fetal neck masses. The mean gestational age at which the fetal neck mass was first detected was 27 ± 6 weeks (range 17-38 weeks). There were seven (39%) male fetuses, nine (50%) female fetuses, and two (11%) fetuses of undetermined sex. The clinical diagnosis was lymphangioma in 14 cases (78%), hemangioma in two (11%), teratoma in one (6%), and congenital goiter in one (6%). The maximum diameter of the fetal neck mass at the first ultrasound examination was 1.8-8.6 cm, and the median diameter was 4.3 (2.5, 6.5) cm. The median mass volume was 17.0 (3.5, 59.0) cm (range 1.0-219.0 cm). The neck mass was cystic in nine cases, a cystic solid mass with compartmentalization in five cases, and a solid mass with a blood flow signal in four cases. Sixteen fetuses were delivered by elective cesarean section, while two were born via induced labor. The average postnatal follow-up time was 27 months, and the longest follow-up was 6 years. There were 13 cases (72%) with a favorable outcome and five (28%) with an unfavorable outcome.
A fetal neck mass is a rare benign lesion. Accurate evaluation of the size and location of the cervical mass by prenatal ultrasound, auxiliary examinations such as magnetic resonance imaging, and assessments of clinical manifestations and related complications are crucial for appropriate prenatal consultation, prognosis assessment, delivery mode selection, and postpartum management. Multidisciplinary treatment is essential for the successful management of fetal cervical masses.
本研究回顾性分析胎儿颈部肿物的产前超声特征及结局，以提高对胎儿颈部肿物的认识，为产前咨询、预后评估、分娩方式选择及临床干预提供依据。
回顾性纳入2018年1月至2023年11月在北京协和医院超声科接受常规产前超声检查或因胎儿颈部肿物诊断转诊至我院的18例患者。检查其产前超声特征及妊娠结局并进行随访。
共18例胎儿颈部肿物。首次发现胎儿颈部肿物时的平均孕周为27±6周（范围17 - 38周）。男胎7例（39%），女胎9例（50%），性别未确定的胎儿2例（11%）。临床诊断为淋巴管瘤14例（78%），血管瘤2例（11%），畸胎瘤1例（6%），先天性甲状腺肿1例（6%）。首次超声检查时胎儿颈部肿物的最大直径为1.8 - 8.6 cm，中位直径为4.3（2.5，6.5） cm。肿物体积中位数为17.0（3.5，59.0） cm（范围1.0 - 219.0 cm）。颈部肿物为囊性9例，分隔状囊实性肿物5例，有血流信号的实性肿物4例。16例胎儿通过选择性剖宫产分娩，2例引产。产后平均随访时间为27个月，最长随访6年。预后良好13例（72%），预后不良5例（28%）。
胎儿颈部肿物是一种罕见的良性病变。产前超声准确评估颈部肿物的大小和位置、磁共振成像等辅助检查以及临床表现和相关并发症的评估对于恰当的产前咨询、预后评估、分娩方式选择及产后管理至关重要。多学科治疗对于胎儿颈部肿物的成功管理必不可少。
