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脂肪细胞大小波动、机械活性脂滴与小窝

Adipocyte size fluctuation, mechano-active lipid droplets and caveolae.

作者信息

Le Lay Soazig, Briand Nolwenn, Dugail Isabelle

机构信息

INSERM SOPAM; U1063; Université d'Angers; IBS-IRIS Rue des Capucins ; Angers, France.

INSERM; UMRS 938; Center de Recherche Saint-Antoine ; Paris, France.

出版信息

Adipocyte. 2014 Dec 17;4(2):158-60. doi: 10.4161/21623945.2014.973774. eCollection 2015 Apr-Jun.

Abstract

Recent data indicate that cell size fluctuation, a key property in adipocyte pathophysiology primarily dependent on lipid storage, is linked to a novel function of lipid droplet organelles acting as mechano-active organelles to regulate cell membrane remodeling and caveolae dynamics.

摘要

最近的数据表明,细胞大小波动是脂肪细胞病理生理学中的一个关键特性,主要依赖于脂质储存,它与脂滴细胞器的一种新功能有关,脂滴细胞器作为机械活性细胞器,可调节细胞膜重塑和小窝动态变化。

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