Ren Da-Jiang, Liu Xiu-Mei, Du Sui-Yong, Sun Tian-Sheng, Zhang Zhi-Cheng, Li Fang
Department of Orthopedic Surgery, Beijing Army General Hospital, Dongcheng District, Beijing 100700, China.
Chin Med J (Engl). 2015 Jul 20;128(14):1893-7. doi: 10.4103/0366-6999.160518.
This study evaluated the efficacy of percutaneous nucleoplasty using coblation technique for the treatment of chronic nonspecific low back pain (LBP), after 5 years of follow-up.
From September 2004 to November 2006, 172 patients underwent percutaneous nucleoplasty for chronic LBP in our department. Forty-one of these patients were followed up for a mean period of 67 months. Nucleoplasty was performed at L3/4 in 1 patient; L4/5 in 25 patients; L5/S1 in 2 patients; L3/4 and L4/5 in 2 patients; L4/5 and L5/S1 in 7 patients; and L3/4, L4/5, and L5/S1 in 4 patients. Patients were assessed preoperatively and at 1 week, 1 year, 3 years, and 5 years postoperatively. Pain was graded using a 10-cm Visual Analogue Scale (VAS) and the percentage reduction in pain score was calculated at each postoperative time point. The Oswestry Disability Index (ODI) was used to assess disability-related to lumbar spine degeneration, and patient satisfaction was assessed using the modified MacNab criteria.
There were significant differences among the preoperative, 1-week postoperative, and 3-year postoperative VAS and ODI scores, but not between the 3- and 5-year postoperative scores. There were no significant differences in age, sex, or preoperative symptoms between patients with effective and ineffective treatment, but there were significant differences in the number of levels treated, Pfirrmann grade of intervertebral disc degeneration, and provocative discography findings between these two groups. Excellent or good patient satisfaction was achieved in 87.9% of patients after 1 week, 72.4% after 1 year, 67.7% after 3 years, and 63.4% at the last follow-up.
Although previously published short- and medium-term outcomes after percutaneous nucleoplasty appeared to be satisfactory, our long-term follow-up results show a significant decline in patient satisfaction over time. Percutaneous nucleoplasty is a safe and simple technique, with therapeutic effectiveness for the treatment of chronic LBP in selected patients. The technique is minimally invasive and can be used as part of a stepwise treatment plan for chronic LBP.
本研究在随访5年后,评估了使用等离子消融技术的经皮髓核成形术治疗慢性非特异性下腰痛(LBP)的疗效。
2004年9月至2006年11月,我科172例患者接受了经皮髓核成形术治疗慢性LBP。其中41例患者接受了平均67个月的随访。1例患者在L3/4节段进行髓核成形术;25例在L4/5节段;2例在L5/S1节段;2例在L3/4和L4/5节段;7例在L4/5和L5/S1节段;4例在L3/4、L4/5和L5/S1节段。在术前以及术后1周、1年、3年和5年对患者进行评估。使用10厘米视觉模拟量表(VAS)对疼痛进行分级,并计算每个术后时间点疼痛评分的降低百分比。采用Oswestry功能障碍指数(ODI)评估与腰椎退变相关的功能障碍,并使用改良的MacNab标准评估患者满意度。
术前、术后1周和术后3年的VAS和ODI评分存在显著差异,但术后3年和5年的评分之间无显著差异。治疗有效和无效的患者在年龄、性别或术前症状方面无显著差异,但两组在治疗节段数、椎间盘退变的Pfirrmann分级以及激发性椎间盘造影结果方面存在显著差异。术后1周87.9%的患者、1年后72.4%的患者、3年后67.7%的患者以及末次随访时63.4%的患者获得了优或良的患者满意度。
尽管先前发表的经皮髓核成形术后短期和中期结果似乎令人满意,但我们的长期随访结果显示患者满意度随时间显著下降。经皮髓核成形术是一种安全、简单的技术,对选定的慢性LBP患者具有治疗效果。该技术微创,可作为慢性LBP逐步治疗计划的一部分。