Esparaz Elizabeth S, Sobel Rachel K
Department of Ophthalmology, Boston University School of Medicine, Boston Medical Center, Boston, Massachusetts, USA.
Curr Opin Ophthalmol. 2015 Jul;26(5):422-8. doi: 10.1097/ICU.0000000000000187.
The decision to stop or continue anticoagulants or antiplatelet therapy for oculoplastic procedures has long been a complicated and serious discussion for surgeons and their patients. Although other specialties have developed evidenced-based algorithms to guide their decision-making our subspecialty remains driven largely by anecdotal information. This article aims to get closer to an evidenced-based approach to perioperative anticoagulant and antiplatelet management.
Over the last few years, new antiplatelet and anticoagulant therapies are on the market with different characteristics in terms of half-life and mechanism of action. It is imperative the contemporary surgeon be well versed in these new medications. Also, new studies have emerged from the vascular literature with specific evidenced-based recommendations for heart and stroke patients. These guidelines need to be weighed with a patient's cardiologist or neurologist.
The article will review the old and new anticoagulant and antiplatelet therapies as well as the recent literature for stroke and cardiac patients to guide the oculoplastic surgeon in this nuanced decision. It will also discuss current practice patterns in light of these new therapies and medical guidelines.
对于眼科整形手术而言,决定停止或继续使用抗凝剂或抗血小板治疗,长期以来一直是外科医生及其患者之间复杂而严肃的讨论话题。尽管其他专科已经制定了循证算法来指导决策,但我们这个亚专科很大程度上仍受传闻信息的驱动。本文旨在更接近一种基于证据的围手术期抗凝和抗血小板管理方法。
在过去几年中,市场上出现了具有不同半衰期和作用机制特点的新型抗血小板和抗凝治疗药物。当代外科医生必须精通这些新药。此外,血管领域的文献中也出现了针对心脏病和中风患者的具体循证建议。这些指南需要与患者的心脏病专家或神经科医生共同权衡。
本文将回顾新旧抗凝和抗血小板治疗方法,以及近期针对中风和心脏病患者的文献,以指导眼科整形医生做出这一微妙的决策。还将根据这些新疗法和医学指南讨论当前的实践模式。