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Quantitative distribution of six amino acids in rat retinal layers.

作者信息

Ross C D, Parli J A, Godfrey D A

机构信息

Department of Physiology, Oral Roberts University, Tulsa, OK 74171.

出版信息

Vision Res. 1989;29(9):1079-84. doi: 10.1016/0042-6989(89)90055-2.

DOI:10.1016/0042-6989(89)90055-2
PMID:2617855
Abstract

Concentrations of glutamate, aspartate, glutamine, glycine, GABA, and taurine were determined in samples microdissected from rat retinal layers and assayed by HPLC. Glutamate and glutamine were relatively high in the inner nuclear (INL) and ganglion cell (GCL) layers; aspartate was relatively high in the outer nuclear layer (ONL), outer plexiform layer, and INL. Distributions of glutamate and aspartate did not correlate well with those of enzymes involved in their metabolism. Glycine and GABA were highest in the inner plexiform layer, with increasing concentrations through the INL, and were relatively high in the GCL. Taurine was highest in the ONL.

摘要

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